Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13836819 | 0.87 | KMT2A (0.49) | SCN9AMEN1KMT2ADHODHPDE10A | |
| SCHEMBL13837207 | 0.84 | ADORA2A (0.45) | SCN9AADORA2APDE10A | |
| SCHEMBL13837206 | 0.82 | MBNL1 (0.44) | SCN9AMAPK10ADORA2AMEN1KMT2A | |
| SCHEMBL13967979 | 0.79 | RAB9A (0.47) | MEN1KMT2A | |
| SCHEMBL8008310 | 0.78 | MAPK14 (0.57) | MAPK14MAPK10ADORA2AMEN1KMT2A | |
| SCHEMBL71619 | 0.76 | MAPK14 (0.81) | MAPK14MAPK10ADORA2AMEN1KMT2A | |
| SCHEMBL29405271 | 0.76 | MAPK14 (0.81) | MAPK14MAPK10ADORA2AMEN1KMT2A | |
| SCHEMBL29596631 | 0.74 | MAPK14 (0.78) | MAPK14MAPK10ADORA2AMEN1KMT2A | |
| SCHEMBL28252524 | 0.74 | MAPK14 (0.78) | MAPK14MAPK10ADORA2AMEN1KMT2A | |
| SCHEMBL29767839 | 0.74 | MAPK14 (0.78) | MAPK14MAPK10ADORA2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952192-B2 | Phosphorylated and branched dihydroxy-pentane-dione (DPD) analogs as quorum sensing inhibitors in bacteria | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2015-02-10 | — | — | US | disclosed |
| US-8952192-B2 | Phosphorylated and branched dihydroxy-pentane-dione (DPD) analogs as quorum sensing inhibitors in bacteria | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2015-02-10 | — | — | US | disclosed |
| US-20120294900-A1 | Phosphorylated and Branched Dihydroxy-Pentane-Dione (DPD) Analogs as Quorum Sensing Inhibitors in Bacteria | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120294900-A1 | Phosphorylated and Branched Dihydroxy-Pentane-Dione (DPD) Analogs as Quorum Sensing Inhibitors in Bacteria | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120294900-A1 | Phosphorylated and Branched Dihydroxy-Pentane-Dione (DPD) Analogs as Quorum Sensing Inhibitors in Bacteria | PGD, DUSP2, PGLS | SCN9A 4688/4885MAPK14 490/4885MAPK10 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.