Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 10/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 9/20 | 0.42 |
| ▸ | GSK3A | P49840 | 6/20 | 0.42 |
| ▸ | GSK3B | P49841 | 6/20 | 0.42 |
| ▸ | CDK8 | P49336 | 4/20 | 0.41 |
| ▸ | MST1R | Q04912 | 2/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | SRPK1 | Q96SB4 | 4/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.41 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | HIPK4 | Q8NE63 | 5/20 | 0.39 |
| ▸ | STK3 | Q13188 | 4/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14319140 | 0.78 | GRM5 (0.48) | RORCCLK4ACVR1GSK3AGSK3B | |
| SCHEMBL14308049 | 0.78 | CLK4 (0.45) | RORCCLK4ACVR1GSK3AGSK3B | |
| SCHEMBL15219108 | 0.76 | RORC (0.44) | RORCCLK4ACVR1GSK3AGSK3B | |
| SCHEMBL16358862 | 0.76 | RORC (0.44) | RORCCLK4ACVR1GSK3AGSK3B | |
| SCHEMBL1464316 | 0.76 | GSK3A (0.49) | RORCCLK4ACVR1GSK3AGSK3B | |
| SCHEMBL14960342 | 0.75 | GSK3A (0.48) | RORCCLK4ACVR1GSK3AGSK3B | |
| SCHEMBL12102188 | 0.75 | ACVR1 (0.47) | RORCCLK4ACVR1GSK3AGSK3B | |
| SCHEMBL3656731 | 0.75 | RORC (0.51) | RORCCLK4ACVR1GSK3AGSK3B | |
| SCHEMBL13170010 | 0.74 | KDM4E (0.56) | CLK4ACVR1GSK3AGSK3BCDK8 | |
| SCHEMBL18425134 | 0.74 | ACVR1 (0.49) | RORCCLK4ACVR1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061652-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-14 | — | — | WO | disclosed |