Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 7/20 | 0.45 |
| ▸ | HIPK4 | Q8NE63 | 5/20 | 0.45 |
| ▸ | STK3 | Q13188 | 4/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.45 |
| ▸ | FLT3 | P36888 | 3/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.45 |
| ▸ | PBK | Q96KB5 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 3/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.45 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.45 |
| ▸ | CDK8 | P49336 | 3/20 | 0.45 |
| ▸ | FLT4 | P35916 | 2/20 | 0.45 |
| ▸ | FRK | P42685 | 2/20 | 0.45 |
| ▸ | MST1R | Q04912 | 2/20 | 0.45 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.45 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14319140 | 0.91 | GRM5 (0.48) | CLK4ACVR1HIPK4STK3AURKB | |
| SCHEMBL14309232 | 0.84 | CLK4 (0.41) | CLK4ACVR1HIPK4STK3AURKB | |
| SCHEMBL14319138 | 0.81 | HCRTR1 (0.41) | CLK4ACVR1HIPK4STK3AURKB | |
| SCHEMBL12102188 | 0.79 | ACVR1 (0.47) | CLK4ACVR1HIPK4STK3AURKB | |
| SCHEMBL1464304 | 0.79 | CNR2 (0.50) | CLK4ACVR1HIPK4STK3AURKB | |
| SCHEMBL13842703 | 0.78 | RORC (0.48) | CLK4ACVR1HIPK4STK3AURKB | |
| SCHEMBL1464316 | 0.76 | GSK3A (0.49) | CLK4ACVR1HIPK4STK3AURKB | |
| SCHEMBL14960342 | 0.74 | GSK3A (0.48) | CLK4ACVR1HIPK4STK3AURKB | |
| SCHEMBL2635287 | 0.72 | TAS2R14 (0.57) | CLK4ACVR1HIPK4STK3AURKB | |
| SCHEMBL13842719 | 0.72 | HTR1A (0.41) | CLK4ACVR1HIPK4STK3AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |