Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11881936 | 0.98 | NAAA (0.50) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL11879157 | 0.98 | NAAA (0.50) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL4425079 | 0.94 | ALDH1A1 (0.48) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL6136741 | 0.86 | — | — | |
| SCHEMBL5821261 | 0.82 | NAAA (0.48) | NAAAEPHX1CA12CA1CA2 | |
| SCHEMBL6161876 | 0.81 | NAAA (0.52) | NAAAEPHX1TSHRALDH1A1HCAR2 | |
| SCHEMBL10451499 | 0.81 | NAAA (0.52) | NAAAEPHX1TSHRALDH1A1HCAR2 | |
| SCHEMBL6161948 | 0.81 | NAAA (0.52) | NAAAEPHX1TSHRALDH1A1HCAR2 | |
| SCHEMBL8753101 | 0.79 | TSHR (0.50) | NAAAEPHX1TSHRALDH1A1HCAR2 | |
| SCHEMBL42860 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4838146-B2 | — | — | 2011-12-14 | — | — | JP | claimed |
| CN-1898245-B | Process for preparing triazolopyrimidines | DOW AGROSCIENCES LLC | 2011-07-20 | — | — | CN | claimed |
| US-7781582-B2 | Process for the preparation of 2-amino-[1,2,4]triazolo[1,5-a]pyrimidines | DOW AGROSCIENCES LLC (US) | 2010-08-24 | — | — | US | claimed |
| EP-2117718-A1 | NOVEL DITHIOCARBAMATE COLLECTORS AND THEIR USE IN THE BENEFICATION OF MINERAL ORE BODIES | CYTEC TECHNOLOGY CORP. (US) | 2009-11-18 | — | — | EP | claimed |
| WO-2008097707-A1 | NOVEL DITHIOCARBAMATE COLLECTORS AND THEIR USE IN THE BENEFICATION OF MINERAL ORE BODIES | CYTEC TECHNOLOGY CORP. (US) | 2008-08-14 | — | — | WO | claimed |
| EP-1699794-B1 | PROCESS FOR THE PREPARATION OF TRIAZOLOPYRIMIDINES | DOW AGROSCIENCES LLC (US) | 2008-01-02 | — | — | EP | claimed |
| US-20070238873-A1 | Process for the Preparation of Triazolopyrimidines | CORTEVA AGRISCIENCE LLC | 2007-10-11 | — | — | US | claimed |
| CN-1898245-A | Process for preparing triazolopyrimidines | DOW AGROSCIENCES LLC (US) | 2007-01-17 | — | — | CN | claimed |
| EP-1699794-A1 | PROCESS FOR THE PREPARATION OF TRIAZOLOPYRIMIDINES | Dow AgroSciences LLC (US) | 2006-09-13 | — | — | EP | claimed |
| EP-1059289-B1 | Process for manufacture of N-alk(en)oxy(or aryloxy)carbonyl isothiocyanates and their derivatives in the presence of N,N-dialkylarylamine catalyst | BAYER AG (US) | 2005-07-27 | — | — | EP | claimed |
| WO-2005063753-A1 | PROCESS FOR THE PREPARATION OF TRIAZOLOPYRIMIDINES | DOW AGROSCIENCES LLC (US) | 2005-07-14 | — | — | WO | claimed |
| EP-2117718-B1 | NOVEL DITHIOCARBAMATE COLLECTORS AND THEIR USE IN THE BENEFICATION OF MINERAL ORE BODIES | CYTEC TECH CORP (US) | 2017-05-10 | — | — | EP | disclosed |
| CN-101605608-B | Dithiocarbamate collectors and their use in mineral processing | CYTEC TECH CORP | 2014-03-12 | — | — | CN | disclosed |
| US-8376142-B2 | Dithiocarbamate collectors and their use in the beneficiation of mineral ore bodies | CYTEC TECHNOLOGY CORP. (US) | 2013-02-19 | — | — | US | disclosed |
| CN-1898245-B | Process for preparing triazolopyrimidines | DOW AGROSCIENCES LLC | 2011-07-20 | — | — | CN | disclosed |
| US-20040259864-A1 | Substituted pyrimidinone derivatives as ligands of integrin receptors | ABBOTT GMBH & CO. KG (DE) | 2004-12-23 | — | — | US | disclosed |
| US-20030171368-A1 | Pyrimidinonesulfamoylureas` | SEITZ WERNER (DE) | 2003-09-11 | — | — | US | disclosed |
| WO-2003066624-A1 | PYRIMIDINONESULFAMOYLUREAS AS INTEGRIN LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2003-08-14 | — | — | WO | disclosed |
| EP-1059289-A1 | Process for manufacture of N-alk(en)oxy(or aryloxy)carbonyl isothiocyanates and their derivatives in the presence of N,N-dialkylarylamine catalyst | Bayer Corporation (US) | 2000-12-13 | — | — | EP | disclosed |
| US-5194673-A | Reacting haloformate and alkali- or alkaline alkaline earth metal thiocyanate in presence of water and catalysts | AMERICAN CYANAMID COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238873-A1 | Process for the Preparation of Triazolopyrimidines | NUDT1, ABL1, DPYD | NAAA 2048/4885EPHX1 3737/4885CA12 3940/4885 |
| US-20040259864-A1 | Substituted pyrimidinone derivatives as ligands of integrin receptors | ITGB3, ITGA5, ITGB5 | NAAA 4550/4885EPHX1 2118/4885CA12 4850/4885 |
| US-20030171368-A1 | Pyrimidinonesulfamoylureas` | ITGB1, ITGA1, ITGAM | NAAA 4802/4885EPHX1 786/4885CA12 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.