Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.42 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12926165 | 0.83 | NOS3 (0.40) | WDR5ALDH1A1KDM4ESMN1; SMN2PRMT6 | |
| SCHEMBL44267 | 0.83 | ALDH1A3 (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL44288 | 0.78 | CHEK1 (0.41) | ALDH1A1KDM4ESMN1; SMN2LMNACYP2C9 | |
| SCHEMBL44576 | 0.78 | WDR5 (0.46) | WDR5TSHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL44612 | 0.76 | TSHR (0.42) | CYP2D6CYP2C19TSHRALDH1A1KDM4E | |
| SCHEMBL39537 | 0.76 | WDR5 (0.46) | WDR5ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL38565 | 0.74 | WDR5 (0.44) | WDR5CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL38703 | 0.73 | WDR5 (0.44) | WDR5CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL44301 | 0.73 | WDR5 (0.66) | WDR5CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL44512 | 0.73 | WDR5 (0.52) | WDR5KDM4ETDP1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009059162-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA ENTERPRISES LIMITED (BS) | 2009-05-07 | — | — | WO | disclosed |