Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 2/20 | 0.34 |
| ▸ | MC5R | P33032 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532077 | 0.84 | SLC6A9 (0.34) | GRM5TP53MAPTESRRGNR1H4 | |
| SCHEMBL5531707 | 0.83 | GRM5 (0.36) | GRM5TP53MAPTESRRGNR1H4 | |
| SCHEMBL1385185 | 0.82 | LMNA (0.38) | LPAR1LPAR5C5AR1KMT2AALDH1A1 | |
| SCHEMBL5189144 | 0.80 | LTB4R2 (0.43) | MAPTLPAR1LPAR5KEAP1MC4R | |
| SCHEMBL3570707 | 0.80 | C5AR1 (0.39) | TP53MAPTLPAR1LPAR5C5AR1 | |
| SCHEMBL1387045 | 0.79 | LPAR1 (0.38) | LPAR1LPAR5C5AR1 | |
| SCHEMBL1385947 | 0.79 | ESRRG (0.36) | TP53MAPTKMT2AESRRGNR1H4 | |
| SCHEMBL1386237 | 0.78 | ESRRG (0.34) | TP53MAPTLPAR1LPAR5ESRRG | |
| SCHEMBL12521072 | 0.78 | TP53 (0.39) | F2F10F7TP53MAPT | |
| SCHEMBL12520932 | 0.77 | DDR1 (0.38) | TP53MAPTC5AR1ESRRGNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4787254-B2 | — | — | 2011-10-05 | — | — | JP | claimed |