Sugi Predict

Sugi Predict / Compounds / SCHEMBL138700

SCHEMBL138700

SCHEMBL138700

C=CC(=O)OCCC[SiH2]C(OCC)OCC

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 9/20 0.54
▸ HPGD P15428 1/20 0.54
▸ ALDH1A1 P00352 4/20 0.50
▸ CYP3A4 P08684 2/20 0.50
▸ TP53 P04637 3/20 0.42
▸ HIF1A Q16665 3/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ THRB P10828 2/20 0.40
▸ ATM Q13315 1/20 0.37
▸ HCAR2 Q8TDS4 3/20 0.33
▸ MAPK1 P28482 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16537094 0.95 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16537215 0.94 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL21066706 0.94 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL7990758 0.93 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16536943 0.90 TSHR (0.49) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL22115859 0.89 TSHR (0.57) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL140136 0.88 TSHR (0.65) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL3914226 0.85 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL140890 0.84 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL676304 0.83 ATM (0.43) TSHRHPGDALDH1A1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 905 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025084741-A1 POLYOLEFIN GRAFT COPOLYMER PRODUCED USING INITIATOR CONTAINING AZIDOFORMATE GROUP AND PRODUCTION METHOD THEREFOR 세종대학교산학협력단 2025-04-24 — — WO claimed
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof BOSTIK SA (FR) 2023-12-05 — — US claimed
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF UNIVERSITE DE RENNES (FR) 2021-06-17 — — US claimed
EP-3802510-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF Bostik SA (FR) 2021-04-14 — — EP claimed
CN-112533910-A Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2021-03-19 — — CN claimed
EP-1675880-B1 METHOD FOR PARTIAL OR TOTAL OXIDATION OF ONE OR SEVERAL THIOCARBONYLTHIO ENDS OF A POLYMER OBTAINED BY RADICAL POLYMERISATION CONTROLLED BY REVERSIBLE ADDITION-CLEAVAGE RHODIA CHIMIE SA (FR) 2019-03-13 — — EP claimed
CN-106867033-B A kind of inorganic matter cladding organic silicon fibre retardant of alternative antimony oxide and the preparation method and application thereof 广东优科艾迪高分子材料有限公司 2019-01-25 — — CN claimed
US-20170298026-A1 ALL PURPOSE RAFT AGENT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2017-10-19 — — US claimed
EP-3204353-A1 ALL PURPOSE RAFT AGENT Commonwealth Scientific and Industrial Research Organisation (AU) 2017-08-16 — — EP claimed
CN-106957396-A A kind of automatically cleaning wear-resisting type organosilicon toughener and preparation method and application 广东优科艾迪高分子材料有限公司 2017-07-18 — — CN claimed
US-20030088028-A1 Methods of polymerization ANTEO TECHNOLOGIES PTY LTD (AU) 2003-05-08 — — US claimed
US-6512081-B1 Synthesis of dithioester chain transfer agents and use of bis(thioacyl) disulfides or dithioesters as chain transfer agents E.I. DUPONT NEMOURS AND COMPANY 2003-01-28 — — US claimed
WO-2002079305-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION POLYMERAT PTY LTD (AU) 2002-10-10 — — WO claimed
US-6376615-B1 USING FREE RADICALS CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) 2002-04-23 — — US claimed
EP-1149075-A1 SYNTHESIS OF DITHIOESTER CHAIN TRANSFER AGENTS AND USE OF BIS(THIOACYL) DISULFIDES OR DITHIOESTERS AS CHAIN TRANSFER AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-10-31 — — EP claimed
US-6291620-B1 Polymer synthesis E. I. DU PONT DE NEMOURS AND COMPANY 2001-09-18 — — US claimed
EP-0791016-B1 POLYMER SYNTHESIS DU PONT (US) 2000-07-12 — — EP claimed
WO-1999005099-A1 SYNTHESIS OF DITHIOESTER CHAIN TRANSFER AGENTS AND USE OF BIS(THIOACYL) DISULFIDES OR DITHIOESTERS AS CHAIN TRANSFER AGENTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-02-04 — — WO claimed
EP-0791016-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-27 — — EP claimed
WO-1996015157-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-05-23 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof MEP1A, MEP1B, ALOX5 TSHR 4885/4885HPGD 278/4885ALDH1A1 581/4885
US-20170298026-A1 ALL PURPOSE RAFT AGENT NPC1L1, RFTN1, SGMS2 TSHR 4058/4885HPGD 1750/4885ALDH1A1 817/4885
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF MEP1A, MEP1B, ALOX5 TSHR 4885/4885HPGD 278/4885ALDH1A1 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.