SCHEMBL13870927

SCHEMBL13870927

COc1cc(OC)c2ccc(-c3cccc(C)c3C)nc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.51
SMN1; SMN2 Q16637 5/20 0.51
ALDH1A1 P00352 5/20 0.51
HPGD P15428 4/20 0.43
MAPT P10636 3/20 0.43
LMNA P02545 2/20 0.43
HTT P42858 1/20 0.43
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
PDE2A O00408 1/20 0.37
PDE6D O43924 1/20 0.37
PDE6A P16499 1/20 0.37
PDE6G P18545 1/20 0.37
PDE6B P35913 1/20 0.37
PDE6C P51160 1/20 0.37
PDE6H Q13956 1/20 0.37
PDE10A Q9Y233 1/20 0.37
POLB P06746 2/20 0.37
NUDT1 P36639 2/20 0.36
PDE3B Q13370 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8888130 0.89 KDM4E (0.57) KDM4ESMN1; SMN2ALDH1A1HPGDMAPT
SCHEMBL16487813 0.84 ALDH1A1 (0.40) KDM4ESMN1; SMN2ALDH1A1HPGDMAPT
SCHEMBL13870929 0.82 KDM4E (0.51) KDM4ESMN1; SMN2ALDH1A1HPGDMAPT
SCHEMBL13870945 0.82 RAD52 (0.41) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL13870925 0.80 KDM4E (0.49) KDM4ESMN1; SMN2ALDH1A1HPGDMAPT
SCHEMBL13870926 0.80 KDM4E (0.49) KDM4ESMN1; SMN2ALDH1A1HPGDMAPT
SCHEMBL13870936 0.79 PDGFRB (0.45) KDM4ESMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL13870910 0.77 KDM4E (0.59) KDM4ESMN1; SMN2ALDH1A1HPGDMAPT
SCHEMBL13870924 0.77 SMN1; SMN2 (0.66) KDM4ESMN1; SMN2ALDH1A1HPGDMAPT
SCHEMBL14500750 0.77 NCF1 (0.49) KDM4ESMN1; SMN2ALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IK, G6PD, EYA2 KDM4E 2874/4885SMN1; SMN2 4169/4885ALDH1A1 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.