SCHEMBL13870945

SCHEMBL13870945

COc1cc2nc(-c3cccc(C)c3C)ccc2c(OC)c1OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MAOA P21397 2/20 0.40
KDM4E B2RXH2 2/20 0.40
USP2 O75604 1/20 0.40
POLB P06746 1/20 0.40
PSMB5 P28074 1/20 0.39
PDE3B Q13370 1/20 0.38
PDE3A Q14432 1/20 0.38
AMY1A P0DUB6 2/20 0.37
SLC10A2 Q12908 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
NUDT1 P36639 2/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16487817 0.84 CD274 (0.39) RAD52MEN1KMT2ANUDT1DHFR
SCHEMBL13870947 0.82 PSMB5 (0.44) RAD52MEN1KMT2AMAOAKDM4E
SCHEMBL13870936 0.82 PDGFRB (0.45) RAD52MEN1KMT2AMAOAKDM4E
SCHEMBL13870927 0.82 KDM4E (0.51) RAD52MEN1KMT2AKDM4EPOLB
SCHEMBL16488129 0.80 PSMB5 (0.43) RAD52MEN1KMT2AMAOAKDM4E
SCHEMBL13870946 0.80 MAOA (0.41) RAD52MEN1KMT2AMAOAKDM4E
SCHEMBL16487813 0.79 ALDH1A1 (0.40) RAD52MEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL13870933 0.77 ALDH1A1 (0.48) MEN1KMT2AMAOAKDM4EUSP2
SCHEMBL13870913 0.76 NUDT1 (0.42) NUDT1DHFR
SCHEMBL13870944 0.76 KATNA1 (0.44) RAD52MAOAKDM4EPOLBPDE3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IK, G6PD, EYA2 RAD52 1820/4885MEN1 1373/4885KMT2A 2208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.