SCHEMBL13870946

SCHEMBL13870946

COc1cc2nc(-c3ccc(C)cc3C)ccc2c(OC)c1OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.41
AMY1A P0DUB6 1/20 0.40
PSMB5 P28074 1/20 0.40
DHFR P00374 1/20 0.40
RAD52 P43351 1/20 0.40
PDGFRB P09619 2/20 0.39
PDGFRA P16234 2/20 0.39
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
TP53 P04637 2/20 0.38
SLC10A2 Q12908 1/20 0.38
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37
TUBB3 Q13509 1/20 0.37
TUBB2A Q13885 1/20 0.37
TUBB8 Q3ZCM7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16488129 0.89 PSMB5 (0.43) MAOAAMY1APSMB5DHFRRAD52
SCHEMBL13870947 0.86 PSMB5 (0.44) MAOAAMY1APSMB5DHFRRAD52
SCHEMBL16487827 0.83 ALPL (0.36) DHFRRAD52TP53ALPLLMNA
SCHEMBL13870937 0.81 PDGFRB (0.47) PDGFRBPDGFRAKDRALPLSMN1; SMN2
SCHEMBL13870926 0.81 KDM4E (0.49) DHFRPDGFRBPDGFRAPDE3BPDE3A
SCHEMBL14500791 0.80 ALDH1A1 (0.47) DHFRRAD52PDGFRBPDGFRAKDR
SCHEMBL13870945 0.80 RAD52 (0.41) MAOAAMY1APSMB5DHFRRAD52
SCHEMBL13870932 0.79 MAOA (0.44) MAOAPSMB5PDGFRBPDGFRAPDE3B
SCHEMBL13870933 0.78 ALDH1A1 (0.48) MAOATP53LMNASMN1; SMN2POLB
SCHEMBL16487816 0.78 ALDH1A1 (0.38) DHFRPDGFRBPDGFRAALPLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-8956737-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2015-02-17 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090085476-A1 RED PHOSPHORESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IK, G6PD, EYA2 MAOA 3884/4885AMY1A 1592/4885PSMB5 4884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.