Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13695952 | 0.94 | LTA4H (0.37) | DGKATSHRLTA4HSMN1; SMN2ALDH1A1 | |
| SCHEMBL14378860 | 0.87 | DGKA (0.46) | DGKATSHRALDH1A1CYP1A2MAPT | |
| SCHEMBL28992799 | 0.84 | LTA4H (0.39) | DGKATSHRLTA4HEPHX2 | |
| SCHEMBL13978973 | 0.82 | DGKA (0.50) | DGKATSHRALDH1A1CYP1A2MAPT | |
| SCHEMBL13897415 | 0.81 | ACHE (0.40) | DGKALTA4HEPHX2 | |
| SCHEMBL28059389 | 0.81 | TSHR (0.36) | DGKATSHRLTA4HALDH1A1MAPT | |
| SCHEMBL15999305 | 0.81 | LMNA (0.43) | DGKALTA4HEPHX2ALDH1A1 | |
| SCHEMBL14201372 | 0.80 | DGKA (0.39) | DGKATSHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL13260789 | 0.79 | ADRA2A (0.50) | TSHRLTA4HSMN1; SMN2CYP2C19MAPT | |
| SCHEMBL13695948 | 0.78 | DNM1 (0.47) | LTA4HSMN1; SMN2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099282-A1 | Functionalized nanoparticles | CIBA SPECIALTY CHEMICALS CORP. | 2009-04-16 | — | — | US | disclosed |