Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.67 |
| ▸ | MMP7 | P09237 | 2/20 | 0.67 |
| ▸ | MMP14 | P50281 | 2/20 | 0.67 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.54 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12548333 | 0.90 | HSD11B1 (0.66) | MMP2MMP7MMP14HSD11B1 | |
| SCHEMBL6129859 | 0.81 | ALDH1A1 (0.62) | HSD11B1 | |
| SCHEMBL941159 | 0.81 | MMP2 (0.73) | MMP2MMP7MMP14MMP1MMP3 | |
| SCHEMBL29091331 | 0.80 | MMP2 (1.00) | MMP2MMP7MMP14MMP1MMP3 | |
| SCHEMBL7273970 | 0.77 | HTT (0.55) | MMP1MMP13HSD11B1 | |
| SCHEMBL28392708 | 0.76 | RECQL (0.73) | MMP2MMP7MMP14MMP1MMP3 | |
| SCHEMBL2703745 | 0.75 | MMP2 (0.55) | MMP2MMP7MMP14MMP1MMP3 | |
| SCHEMBL11225865 | 0.74 | KMT2A (0.69) | MMP2MMP7MMP14MMP1MMP3 | |
| SCHEMBL293991 | 0.74 | PSIP1 (0.74) | MMP2MMP7MMP14MMP1MMP3 | |
| SCHEMBL5134257 | 0.74 | PSIP1 (0.74) | MMP2MMP7MMP14MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099249-A1 | THERAPEUTIC LACTAMS | ALLERGAN, INC. | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099249-A1 | THERAPEUTIC LACTAMS | CLPP, NOTUM, PEPD | MMP2 539/4885MMP7 958/4885MMP14 1887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.