SCHEMBL13875347

SCHEMBL13875347

CN1CCN(C(=O)C(=O)c2ccccc2)C1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.51
CHRM1 P11229 2/20 0.51
MAPT P10636 1/20 0.51
POLB P06746 3/20 0.49
KDM4E B2RXH2 1/20 0.47
GRM5 P41594 1/20 0.45
KMT2A Q03164 2/20 0.44
EPHX2 P34913 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
GAA P10253 2/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
MEN1 O00255 1/20 0.43
KCNH2 Q12809 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8566690 0.89 HPGD (0.62) HPGDCHRM1MAPTPOLBKDM4E
SCHEMBL12018338 0.83 CES2 (0.56) HPGDCHRM1MAPTKMT2AGAA
SCHEMBL19380443 0.76 PHGDH (0.66) HPGDCHRM1MAPTPOLBKDM4E
SCHEMBL12018348 0.76 CES2 (0.47) HPGDCHRM1MAPTPOLBKMT2A
SCHEMBL12489727 0.76 HPGD (0.62) HPGDPOLBKMT2AGAACES2
SCHEMBL8382619 0.75 CYP2C19 (0.51) HPGDCHRM1MAPTKMT2AL3MBTL1
SCHEMBL4143496 0.74 POLB (0.80) HPGDPOLBGRM5KMT2AL3MBTL1
SCHEMBL5564719 0.74 HPGD (0.66) HPGDPOLBKMT2AGAAMEN1
SCHEMBL28919752 0.74 MAPT (0.63) MAPTPOLBKMT2AMEN1
SCHEMBL13875346 0.72 ACHE (0.70) HPGDGRM5KMT2AGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8414982-B2 Process for the production of strongly adherent coatings BASF SE (DE) 2013-04-09 US disclosed
US-20090092768-A1 Process for the Production of Strongly Adherent Coatings CIBA SPECIALTY CHEMICALS CORP. 2009-04-09 US disclosed