Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.38 |
| ▸ | RXRB | P28702 | 4/20 | 0.38 |
| ▸ | RXRG | P48443 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CD69 | Q07108 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079952 | 0.87 | MLYCD (0.40) | MEN1KMT2ADRD4OPRM1SIGMAR1 | |
| SCHEMBL20187534 | 0.77 | CACNA2D1 (0.49) | DRD4OPRM1SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL1387794 | 0.77 | MEN1 (0.42) | MEN1KMT2AOPRM1ALDH1A1KDM4E | |
| SCHEMBL1387733 | 0.73 | ALDH1A1 (0.43) | MEN1KMT2ADRD4ALDH1A1KDM4E | |
| SCHEMBL9080067 | 0.71 | ALDH1A1 (0.42) | MEN1KMT2ADRD4ALDH1A1KDM4E | |
| SCHEMBL1387584 | 0.70 | NAMPT (0.36) | KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL22403100 | 0.70 | CACNA2D1 (0.45) | MEN1KMT2ADRD4OPRM1SIGMAR1 | |
| SCHEMBL10102506 | 0.70 | TSHR (0.41) | MEN1KMT2AELANEDRD4CD69 | |
| SCHEMBL1387663 | 0.69 | S1PR1 (0.63) | MEN1KMT2AALDH1A1 | |
| SCHEMBL20199981 | 0.68 | DRD4 (0.43) | TACR1DRD4OPRM1SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H08511809-A | — | — | 1996-12-10 | — | — | JP | claimed |
| US-5573752-A | Aromatic amide compounds and metal chelates thereof | BRACCO INTERNATIONAL B.V. | 1996-11-12 | — | — | US | claimed |
| EP-0702677-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO International B.V. (NL) | 1996-03-27 | — | — | EP | claimed |
| WO-1995027705-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-19 | — | — | WO | claimed |
| US-5573752-A | Aromatic amide compounds and metal chelates thereof | BRACCO INTERNATIONAL B.V. | 1996-11-12 | — | — | US | disclosed |
| WO-1995027705-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-19 | — | — | WO | disclosed |