Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 8/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3993826 | 0.86 | RORC (0.42) | KDM4EMAPTALDH1A1PCSK9GAA | |
| SCHEMBL4257184 | 0.84 | PCSK9 (0.36) | NR4A2BRD4KDM4ECYP1A2PKM | |
| SCHEMBL3990181 | 0.84 | RORC (0.39) | NR4A2KMT2APCSK9 | |
| SCHEMBL3994459 | 0.83 | PCSK9 (0.51) | CYP2C19PCSK9 | |
| SCHEMBL3972624 | 0.78 | POLB (0.55) | NR4A2MAPTALDH1A1KMT2A | |
| SCHEMBL3986985 | 0.73 | ABCG2 (0.47) | NR4A2KDM4EALDH1A1GAA | |
| SCHEMBL3995936 | 0.73 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL3989803 | 0.72 | ABCG2 (0.39) | NR4A2MAPTALDH1A1KMT2AGAA | |
| SCHEMBL3989840 | 0.72 | MTNR1A (0.39) | NR4A2 | |
| SCHEMBL3990318 | 0.72 | NR4A2 (0.35) | NR4A2KDM4EMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050235-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |