Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 8/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3990318 | 0.94 | NR4A2 (0.35) | MTNR1AMTNR1BNR4A2ABCG2 | |
| SCHEMBL3986985 | 0.89 | ABCG2 (0.47) | MTNR1AMTNR1BNR4A2ABCG2NQO2 | |
| SCHEMBL3995936 | 0.83 | ALDH1A1 (0.44) | MTNR1AMTNR1BABCG2NQO2 | |
| SCHEMBL3996013 | 0.82 | KDR (0.41) | NR4A2CA12CA9 | |
| SCHEMBL3973248 | 0.80 | KDM4E (0.42) | NR4A2CA12CA9 | |
| SCHEMBL3972624 | 0.79 | POLB (0.55) | NR4A2 | |
| SCHEMBL4257184 | 0.78 | PCSK9 (0.36) | NR4A2 | |
| SCHEMBL4259652 | 0.78 | NR4A2 (0.34) | NR4A2ABCG2 | |
| SCHEMBL3992240 | 0.75 | POLB (0.38) | NR4A2CA12CA9 | |
| SCHEMBL3992947 | 0.75 | POLB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065382-A1 | CGRP antagonists | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |