Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937204 | 0.90 | MAOA (0.49) | ACHEBCHESCN1ASCN8AMAOA | |
| SCHEMBL8937220 | 0.89 | HRH1 (0.39) | ACHEBCHESCN1ASCN8AMAOA | |
| SCHEMBL8939062 | 0.88 | HRH1 (0.41) | SCN1ASCN8AMAOAMAOBHRH1 | |
| SCHEMBL8937227 | 0.87 | ACHE (0.43) | ACHESCN1ASCN8ACCR3ENPP2 | |
| SCHEMBL8937216 | 0.86 | HRH1 (0.42) | SCN1ASCN8AMAOAMAOBHRH1 | |
| SCHEMBL8937221 | 0.85 | SCN8A (0.41) | SCN8AHTR1DCHRM2CHRM3DRD2 | |
| SCHEMBL8987720 | 0.85 | BCHE (0.43) | ACHEBCHESCN1ASCN8AMAOA | |
| SCHEMBL8984820 | 0.85 | KMT2A (0.43) | ACHEBCHESCN1ASCN8ACHRM2 | |
| SCHEMBL8937187 | 0.84 | HRH1 (0.39) | DRD2HRH1CCR3 | |
| SCHEMBL8937197 | 0.82 | DRD2 (0.42) | MAOAMAOBDRD2HRH1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093518-A1 | Piperidinyl-substituted isoquinolone derivatives | SANOFI-AVENTIS (FR) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093518-A1 | Piperidinyl-substituted isoquinolone derivatives | MYLK2, MYLK, RHOT2 | ACHE 3559/4885BCHE 3883/4885SCN1A 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.