Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 7/20 | 0.39 |
| ▸ | PYGM | P11217 | 5/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891413 | 0.88 | PYGL (0.52) | PYGLPYGMF11RIPK1GAA | |
| SCHEMBL4063960 | 0.76 | PYGL (0.57) | PYGLPYGM | |
| SCHEMBL13878918 | 0.76 | PYGL (0.57) | PYGLPYGM | |
| SCHEMBL14641138 | 0.74 | PYGL (0.57) | PYGLPYGMF11RIPK1GAA | |
| SCHEMBL4066845 | 0.71 | GAA (0.45) | PYGLPYGMRIPK1GAA | |
| SCHEMBL13878893 | 0.71 | GAA (0.45) | PYGLPYGMRIPK1GAA | |
| SCHEMBL10233313 | 0.69 | GAA (0.49) | GAA | |
| SCHEMBL13891430 | 0.69 | PYGL (0.50) | PYGLPYGMF11RIPK1GAA | |
| SCHEMBL13271669 | 0.69 | PYGL (0.34) | PYGLGAA | |
| SCHEMBL2608542 | 0.69 | AVPR1A (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099176-A1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PROSIDION LIMITED (GB) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099176-A1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES | PC, GOT2, PDK1 | PYGL 104/4885PYGM 229/4885F11 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.