Purine

Purine

SCHEMBL1389669

[KH].c1ncc2[nH]cnc2n1

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
KDM4E B2RXH2 1/20 0.45
PI4KA P42356 2/20 0.38
PI4K2B Q8TCG2 2/20 0.38
PI4K2A Q9BTU6 2/20 0.38
PI4KB Q9UBF8 2/20 0.38
LRRK2 Q5S007 2/20 0.38
LMNA P02545 2/20 0.38
DRD3 P35462 1/20 0.38
XDH P47989 1/20 0.38
G6PD P11413 1/20 0.36
CDK2 P24941 3/20 0.36
RXFP1 Q9HBX9 1/20 0.36
METAP2 P50579 1/20 0.35
METAP1 P53582 1/20 0.35
PDPK1 O15530 2/20 0.34
TP53 P04637 2/20 0.34
CHEK1 O14757 1/20 0.34
AURKA O14965 1/20 0.34
CHEK2 O96017 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Purine SCHEMBL6421380 0.98 ALDH1A1 (0.47) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL3158 0.98
Purine SCHEMBL29365913 0.98
Purine SCHEMBL29703771 0.98 ALDH1A1 (0.47) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL30862524 0.98
Purine SCHEMBL2120554 0.98 ALDH1A1 (0.47) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL712798 0.95 ALDH1A1 (0.45) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL7787140 0.95 ALDH1A1 (0.45) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL37120 0.95 ALDH1A1 (0.45) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A
Purine SCHEMBL6438164 0.95 ALDH1A1 (0.45) ALDH1A1KDM4EPI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115198318-A Electric contact tube and manufacturing method thereof 四川华丰科技股份有限公司 2022-10-18 CN claimed
CN-115198318-A Electric contact tube and manufacturing method thereof 四川华丰科技股份有限公司 2022-10-18 CN disclosed
CN-106342838-B A kind of plant growth regualting composition, preparation and its application 四川国光农化股份有限公司 2018-11-27 CN disclosed
CN-106342838-A Compound for regulating plant growth, and preparation and application thereof 四川国光农化股份有限公司 2017-01-25 CN disclosed
EP-2404926-B1 Preparation of 2-chloro-9-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-adenine SCINOPHARM TAIWAN LTD (TW) 2014-08-20 EP disclosed
US-8648188-B2 Preparation of 2-chloro-9-(2′-deoxy-2′-fluoro-β-D-arabinofuranosyl)-adenine SCINOPHARM TAIWAN, LTD. (TW) 2014-02-11 US disclosed
US-20120010397-A1 Preparation of 2-chloro-9-(2'-deoxy-2'-fluoro-Beta-D-arabinofuranosyl)-adenine SCINOPHARM TAIWAN LTD. 2012-01-12 US disclosed
EP-2404926-A1 Preparation of 2-chloro-9-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-adenine ScinoPharm Taiwan, Ltd. (TW) 2012-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010397-A1 Preparation of 2-chloro-9-(2'-deoxy-2'-fluoro-Beta-D-arabinofuranosyl)-adenine HPRT1, TYMP, MTAP ALDH1A1 736/4885KDM4E 983/4885PI4KA 3118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.