Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 5/20 | 0.41 |
| ▸ | MMP9 | P14780 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898761 | 0.85 | NR3C1 (0.37) | MMP1NR3C1LMNAMMP13MMP9 | |
| SCHEMBL6813135 | 0.83 | MMP1 (0.67) | MMP1NR3C1MMP13MMP9MMP2 | |
| SCHEMBL6873149 | 0.80 | MMP1 (0.70) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL13898999 | 0.79 | MMP1 (0.46) | MMP1NR3C1MMP13MMP9MMP2 | |
| SCHEMBL13898985 | 0.79 | NR3C1 (0.43) | MMP1NR3C1LMNAMMP13MMP9 | |
| SCHEMBL13898717 | 0.78 | MMP1 (0.61) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL6813465 | 0.78 | MMP1 (0.55) | MMP1NR3C1LMNAMMP13MAPT | |
| SCHEMBL13898990 | 0.76 | MMP1 (0.58) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL6870820 | 0.76 | MMP1 (0.58) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL3987272 | 0.76 | MMP1 (0.68) | MMP1MMP13MMP9MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |