Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 11/20 | 0.74 |
| ▸ | MMP13 | P45452 | 6/20 | 0.65 |
| ▸ | MMP2 | P08253 | 5/20 | 0.65 |
| ▸ | MMP14 | P50281 | 5/20 | 0.65 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.65 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.65 |
| ▸ | MMP1 | P03956 | 6/20 | 0.65 |
| ▸ | MMP8 | P22894 | 6/20 | 0.65 |
| ▸ | MMP9 | P14780 | 4/20 | 0.65 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.65 |
| ▸ | MMP16 | P51512 | 2/20 | 0.61 |
| ▸ | MMP7 | P09237 | 2/20 | 0.60 |
| ▸ | MMP12 | P39900 | 2/20 | 0.60 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.54 |
| ▸ | BMP1 | P13497 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7340897 | 0.92 | MMP3 (0.76) | MMP3MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL26781503 | 0.90 | MMP3 (0.76) | MMP3MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL3912945 | 0.86 | MMP8 (0.81) | MMP3MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL13898772 | 0.86 | MMP1 (0.66) | MMP3MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL598146 | 0.86 | MMP3 (0.79) | MMP3MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL3913258 | 0.85 | MMP3 (0.57) | MMP3MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL7350210 | 0.85 | MMP3 (1.00) | MMP3MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL3913506 | 0.84 | MEP1B (0.76) | MMP3MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL7348184 | 0.84 | MMP3 (0.82) | MMP3MMP13MMP2MMP14ADAMTS4 | |
| SCHEMBL3924379 | 0.83 | MMP1 (0.62) | MMP3MMP13MMP2MMP14MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |