Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 8/20 | 0.81 |
| ▸ | MMP2 | P08253 | 8/20 | 0.81 |
| ▸ | MMP1 | P03956 | 7/20 | 0.81 |
| ▸ | MMP14 | P50281 | 7/20 | 0.81 |
| ▸ | MMP13 | P45452 | 7/20 | 0.81 |
| ▸ | MMP9 | P14780 | 6/20 | 0.81 |
| ▸ | MMP16 | P51512 | 3/20 | 0.81 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.61 |
| ▸ | MMP7 | P09237 | 2/20 | 0.56 |
| ▸ | MMP12 | P39900 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | MMP3 | P08254 | 8/20 | 0.55 |
| ▸ | BMP1 | P13497 | 2/20 | 0.55 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.50 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913506 | 0.90 | MEP1B (0.76) | MMP8MMP2MMP1MMP14MMP13 | |
| SCHEMBL13898772 | 0.90 | MMP1 (0.66) | MMP8MMP2MMP1MMP14MMP13 | |
| SCHEMBL12508073 | 0.90 | MMP2 (0.81) | MMP8MMP2MMP1MMP14MMP13 | |
| SCHEMBL1133828 | 0.90 | MMP2 (1.00) | MMP8MMP2MMP1MMP14MMP13 | |
| SCHEMBL1134063 | 0.89 | MMP8 (0.83) | MMP8MMP2MMP1MMP14MMP13 | |
| SCHEMBL1133744 | 0.88 | MMP8 (0.81) | MMP8MMP2MMP1MMP14MMP13 | |
| SCHEMBL1133865 | 0.88 | MMP8 (0.81) | MMP8MMP2MMP1MMP14MMP13 | |
| SCHEMBL12418980 | 0.88 | MMP8 (0.81) | MMP8MMP2MMP1MMP14MMP13 | |
| SCHEMBL13899003 | 0.86 | MMP3 (0.74) | MMP8MMP2MMP1MMP14MMP13 | |
| SCHEMBL3917613 | 0.86 | MMP1 (0.61) | MMP8MMP2MMP1MMP14MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-20050282905-A1 | Hydroxamic acid derivative and mmp inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2005-12-22 | — | — | US | disclosed |
| EP-1466899-A1 | HYDROXAMIC ACID DERIVATIVE AND MMP INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282905-A1 | Hydroxamic acid derivative and mmp inhibitor containing the same as active ingredient | MMP13, MMP3, MMP2 | MMP8 19/4885MMP2 3/4885MMP1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.