Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27661293 | 1.00 | TSHR (0.55) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL41489 | 0.98 | TSHR (0.56) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL294789 | 0.93 | TSHR (0.59) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL2943884 | 0.91 | TSHR (0.62) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL16026753 | 0.91 | TSHR (0.62) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL719879 | 0.91 | TSHR (0.62) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL15389940 | 0.91 | TSHR (0.62) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL15389725 | 0.91 | TSHR (0.62) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL12504625 | 0.91 | TSHR (0.62) | TSHRTHRBTDP1POLBAPEX1 | |
| SCHEMBL12504621 | 0.91 | TSHR (0.62) | TSHRTHRBTDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906354-B2 | Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes | BRUKER BIOSPIN CORPORATION (US) | 2014-12-09 | — | — | US | claimed |
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | BRUKER BIOSPIN CORPORATION | 2012-03-08 | — | — | US | claimed |
| US-20100034748-A1 | Molecular imaging probes based on loaded reactive nano-scale latex | QUANTUM MEDICAL HOLDINGS, LLC | 2010-02-11 | — | — | US | claimed |
| WO-2010016858-A2 | MOLECULAR IMAGING PROBES | CARESTREAM HEALTH, INC. (US) | 2010-02-11 | — | — | WO | claimed |
| EP-2004713-A2 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES | Carestream Health, Inc. (US) | 2008-12-24 | — | — | EP | claimed |
| US-20080181965-A1 | Loaded latex optical molecular imaging probes | QUANTUM MEDICAL HOLDINGS, LLC | 2008-07-31 | — | — | US | claimed |
| WO-2007120579-A2 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES | CARESTREAM HEALTH, INC. (US) | 2007-10-25 | — | — | WO | claimed |
| US-20050079506-A1 | Filled, biological microarray and method for use | EASTMAN KODAK COMPANY | 2005-04-14 | — | — | US | claimed |
| US-20050064431-A1 | Biological microarray comprising polymer particles and method of use | EASTMAN KODAK COMPANY | 2005-03-24 | — | — | US | claimed |
| US-20050054815-A1 | Stabilized polymer beads and method of preparation | EASTMAN KODAK COMPANY | 2005-03-10 | — | — | US | claimed |
| US-8906354-B2 | Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes | BRUKER BIOSPIN CORPORATION (US) | 2014-12-09 | — | — | US | disclosed |
| US-8834846-B2 | Fluorescent NIRF activatable probes for disease detection | BRUKER BIOSPIN CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | BRUKER BIOSPIN CORPORATION | 2012-03-08 | — | — | US | disclosed |
| US-20110293529-A1 | FLUORESCENT NIRF ACTIVATABLE PROBES FOR DISEASE DETECTION | BRUKER BIOSPIN CORPORATION | 2011-12-01 | — | — | US | disclosed |
| EP-1352756-B1 | Ink recording element containing stabilized polymeric particles | EASTMAN KODAK CO (US) | 2011-09-21 | — | — | EP | disclosed |
| US-6554419-B2 | Loading a printer that is responsive to digital data signals with recording element of a support having an image-receiving layer made of porous polymeric particles in a polymeric binder | EASTMAN KODAK COMPANY | 2003-04-29 | — | — | US | disclosed |
| US-6541103-B2 | Support with an image-receiving layer of porous polymers of ethylenically unsaturated and cationic group containing monomers | EASTMAN KODAK COMPANY | 2003-04-01 | — | — | US | disclosed |
| US-20030044581-A1 | Ink jet recording element | EASTMAN KODAK COMPANY | 2003-03-06 | — | — | US | disclosed |
| US-20020176966-A1 | Ink jet printing method | EASTMAN KODAK COMPANY | 2002-11-28 | — | — | US | disclosed |
| EP-1245401-A2 | Ink jet recording element and printing method | EASTMAN KODAK COMPANY (US) | 2002-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080181965-A1 | Loaded latex optical molecular imaging probes | MLX, LOXL1, EPX | TSHR 4745/4885THRB 4559/4885TDP1 1546/4885 |
| US-20100034748-A1 | Molecular imaging probes based on loaded reactive nano-scale latex | CLTA, COPE, CD68 | TSHR 2826/4885THRB 2971/4885TDP1 987/4885 |
| US-20050064431-A1 | Biological microarray comprising polymer particles and method of use | CD68, EPCAM, STUB1 | TSHR 2457/4885THRB 2662/4885TDP1 1782/4885 |
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | LASP1, LSS, SELL | TSHR 4670/4885THRB 4793/4885TDP1 1705/4885 |
| US-20110293529-A1 | FLUORESCENT NIRF ACTIVATABLE PROBES FOR DISEASE DETECTION | CTSF, ENGASE, DNTT | TSHR 3525/4885THRB 3363/4885TDP1 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.