Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.70 |
| ▸ | AR | P10275 | 5/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13929945 | 0.91 | ABCB11 (0.73) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11127170 | 0.90 | PGR (0.74) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11262672 | 0.90 | PGR (0.74) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11127550 | 0.90 | PGR (0.74) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11070636 | 0.90 | PGR (0.74) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11127169 | 0.90 | PGR (0.74) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11236326 | 0.89 | PGR (0.72) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11126579 | 0.89 | PGR (0.72) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11236322 | 0.89 | PGR (0.72) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11880720 | 0.89 | PGR (0.74) | PGRARABCB11CYP3A4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048221-A1 | Conjugates with Anti-Inflammatory Activity | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2009-02-19 | — | — | US | disclosed |
| US-20090048221-A1 | Conjugates with Anti-Inflammatory Activity | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. (HR) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048221-A1 | Conjugates with Anti-Inflammatory Activity | MPO, EPX, NOD1 | PGR 643/4885AR 1862/4885ABCB11 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.