Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL3699405

N.c1ccc(CN2CCCC2)cc1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.77
HRH3 Q9Y5N1 3/20 0.70
MC4R P32245 1/20 0.63
HRH4 Q9H3N8 1/20 0.61
DRD4 P21917 1/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2C19 P33261 1/20 0.61
LMNA P02545 1/20 0.61
POLB P06746 1/20 0.61
ALDH1A1 P00352 2/20 0.59
KDM4E B2RXH2 1/20 0.59
SLC6A3 Q01959 1/20 0.59
ACHE P22303 1/20 0.59
MBTD1 Q05BQ5 1/20 0.57
L3MBTL3 Q96JM7 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
PRMT6 Q96LA8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13952 0.98 SIGMAR1 (0.81) SIGMAR1HRH3MC4RHRH4DRD4
SCHEMBL1777747 0.98 SIGMAR1 (0.81) SIGMAR1HRH3MC4RHRH4DRD4
SCHEMBL26532 0.95 SIGMAR1 (0.77) SIGMAR1HRH3MC4RHRH4DRD4
SCHEMBL688047 0.95 SIGMAR1 (0.77) SIGMAR1HRH3MC4RHRH4DRD4
Bromide SCHEMBL10447698 0.95 SIGMAR1 (0.77) SIGMAR1HRH3MC4RHRH4DRD4
SCHEMBL8327 0.95 SIGMAR1 (0.77) SIGMAR1HRH3MC4RHRH4DRD4
SCHEMBL11141692 0.95 SIGMAR1 (0.77) SIGMAR1HRH3MC4RHRH4DRD4
SCHEMBL11585348 0.95 SIGMAR1 (0.77) SIGMAR1HRH3MC4RHRH4DRD4
Hydrochloric Acid SCHEMBL7409551 0.93 SIGMAR1 (0.74) SIGMAR1HRH3MC4RHRH4DRD4
Bromide SCHEMBL10730905 0.93 SIGMAR1 (0.74) SIGMAR1HRH3MC4RHRH4DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100168490-A1 METHOD FOR PREPARATION OF AN ALUMINOSILICATE WITH FERRIERITE STRUCTURE FROM GELS CONTAINING TETRAMETHYLAMMONIUM AND BENZYLMETHYLPYRROLIDINE, AND USES THEREOF CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) 2010-07-01 US disclosed
EP-2133309-A1 METHOD FOR PREPARATION OF AN ALUMINOSILICATE WITH FERRIERITE STRUCTURE FROM GELS CONTAINING TETRAMETHYL AMMONIUM AND BENZYLMETHYLPYRROLIDINE, AND USES THEREOF Consejo Superior De Investigaciones Científicas (ES) 2009-12-16 EP disclosed