Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732035 | 0.98 | CYP2D6 (0.41) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL11867934 | 0.85 | GABRA1 (0.38) | KDM4EALDH1A1HPGDCYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL28319945 | 0.80 | KDM4E (0.44) | KDM4EACHEBCHE | |
| Hydrochloric Acid SCHEMBL11725090 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1038673 | 0.78 | KDM4E (0.41) | KDM4EACHEBCHE | |
| Bromide SCHEMBL14811730 | 0.77 | KDM4E (0.40) | KDM4ERAB9ASMN1; SMN2NPC1ACHE | |
| Hydrochloric Acid SCHEMBL6892436 | 0.75 | HDAC8 (0.46) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3479356 | 0.73 | SMN1; SMN2 (0.40) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| Bromide SCHEMBL11692702 | 0.73 | TP53 (0.48) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL31304100 | 0.73 | HDAC8 (0.47) | KDM4EALDH1A1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218234-A1 | PARAFFIN WAX DISPERSANT | CHAMPIONX LLC | 2024-07-04 | — | — | US | disclosed |
| WO-2024137469-A2 | PARAFFIN WAX DISPERSANT | CHAMPIONX LLC (US) | 2024-06-27 | — | — | WO | disclosed |
| US-20240199955-A1 | CORROSION INHIBITOR HAVING SILICA NANOPARTICLES | CHAMPIONX LLC | 2024-06-20 | — | — | US | disclosed |
| WO-2024124129-A1 | CORROSION INHIBITOR HAVING SILICA NANOPARTICLES | CHAMPIONX LLC (US) | 2024-06-13 | — | — | WO | disclosed |
| EP-4381024-A1 | POLYAMINE-POLYESTERS AS CORROSION INHIBITION | Ecolab USA, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| US-11993744-B2 | Solid paraffin inhibitor and corrosion inhibitor compositions | CHAMPIONX USA INC. (US) | 2024-05-28 | — | — | US | disclosed |
| US-20240117239-A1 | COMBINATION PRODUCTS CONTAINING ANTI-AGGLOMERANT LOW DOSE HYDRATE INHIBITORS AND CORROSION INHIBITORS WITH IMPROVED CORROSION RESISTANCE | CHAMPIONX LLC | 2024-04-11 | — | — | US | disclosed |
| US-20240093090-A1 | CORROSION INHIBITOR COMPOSITIONS AND METHODS OF USING THE SAME | CHAMPIONX USA INC. (US) | 2024-03-21 | — | — | US | disclosed |
| US-11932795-B2 | Aromatic amine epoxide adducts for corrosion inhibition | ECOLAB USA INC. (US) | 2024-03-19 | — | — | US | disclosed |
| WO-2024054812-A2 | COMBINATION PRODUCTS CONTAINING ANTI-AGGLOMERANT LOW DOSE HYDRATE INHIBITORS AND CORROSION INHIBITORS WITH IMPROVED CORROSION RESISTANCE | CHAMPIONX LLC (US) | 2024-03-14 | — | — | WO | disclosed |
| WO-2014210166-A1 | EPOXIDE-BASED HYDROGEN SULFIDE SCAVENGERS | ECOLAB USA INC. (US) | 2014-12-31 | — | — | WO | disclosed |
| US-20140179568-A1 | Method of Using Dithiazines and Derivatives Thereof in the Treatment of Wells | BAKER HUGHES HOLDINGS LLC | 2014-06-26 | — | — | US | disclosed |
| WO-2014089002-A1 | PURIFYING AQUEOUS MIXTURES DERIVED FROM HYDROCARBON PRODUCTION PROCESSES | PAN ASIAN CHEMICALS INC. (US) | 2014-06-12 | — | — | WO | disclosed |
| WO-2013043491-A1 | METHOD OF USING DITHIAZINES AND DERIVATIVES THEREOF IN THE TREATMENT OF WELLS | BAKER HUGHES INCORPORATED (US) | 2013-03-28 | — | — | WO | disclosed |
| US-8354361-B2 | Method of using dithiazines and derivatives thereof in the treatment of wells | BAKER HUGHES INCORPORATED (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120010110-A1 | Method of Using Dithiazines and Derivatives Thereof in the Treatment of Wells | BAKER HUGHES HOLDINGS LLC | 2012-01-12 | — | — | US | disclosed |
| US-8022018-B2 | Quaternized dithiazines and method of using same in treatment of wells | BAKER HUGHES INCORPORATED (US) | 2011-09-20 | — | — | US | disclosed |
| US-8022017-B2 | Method of using dithiazine to inhibit corrosion | BAKER HUGHES INCORPORATED (US) | 2011-09-20 | — | — | US | disclosed |
| US-20110152131-A1 | Method of Using Dithiazines and Derivatives Thereof in the Treatment of Wells | BAKER HUGHES HOLDINGS LLC | 2011-06-23 | — | — | US | disclosed |
| US-20110152137-A1 | METHOD OF USING CORROSION INHIBITORS DERIVED FROM SPENT FLUIDS IN THE TREATMENT OF WELLS | BAKER HUGHES HOLDINGS LLC | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010110-A1 | Method of Using Dithiazines and Derivatives Thereof in the Treatment of Wells | TST, GSS, NDUFS5 | ACHE 4339/4885KDM4E 3641/4885ALDH1A1 2320/4885 |
| US-20110152131-A1 | Method of Using Dithiazines and Derivatives Thereof in the Treatment of Wells | F12, ALOX5, FFAR3 | ACHE 4605/4885KDM4E 3752/4885ALDH1A1 3427/4885 |
| US-11932795-B2 | Aromatic amine epoxide adducts for corrosion inhibition | ITGA8, ADGRE5, CD59 | ACHE 548/4885KDM4E 722/4885ALDH1A1 226/4885 |
| US-11993744-B2 | Solid paraffin inhibitor and corrosion inhibitor compositions | TFPI, CTCF, ATR | ACHE 277/4885KDM4E 131/4885ALDH1A1 3071/4885 |
| US-20140179568-A1 | Method of Using Dithiazines and Derivatives Thereof in the Treatment of Wells | TST, GSS, NDUFS5 | ACHE 4339/4885KDM4E 3641/4885ALDH1A1 2320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.