Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29382911 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDHTTSMN1; SMN2GRIN2D | |
| SCHEMBL6448297 | 0.86 | ALDH1A1 (0.55) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13382332 | 0.85 | ALDH1A1 (0.51) | ALDH1A1HPGDHTTSMN1; SMN2GRIN2D | |
| SCHEMBL23478605 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HPGDHTTSMN1; SMN2POLB | |
| SCHEMBL2093266 | 0.84 | ALDH1A1 (0.58) | ALDH1A1HPGDGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5032627 | 0.84 | GRIN2D (0.60) | ALDH1A1HTTSMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL2093262 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HPGDSMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL1395802 | 0.82 | POLB (0.58) | ALDH1A1HPGDHTTSMN1; SMN2POLB | |
| SCHEMBL16500999 | 0.82 | CETP (0.61) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30136232 | 0.82 | POLB (0.58) | ALDH1A1HPGDHTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | claimed |
| CN-115490724-B | Organic phosphine compound based on cycloalkane skeleton and use thereof | 浙江大学 | 2025-04-01 | — | — | CN | disclosed |
| US-20240317727-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | DUKE UNIVERSITY | 2024-09-26 | — | — | US | disclosed |
| US-20230357208-A1 | MYST FAMILY HISTONE ACETYLTRANSFERASE INHIBITORS | Epizyme, Inc. (US) | 2023-11-09 | — | — | US | disclosed |
| US-11807641-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2023-11-07 | — | — | US | disclosed |
| US-20230234967-A1 | Fused Azole Heterocycles as AHR Antagonists | SAIL BIOMEDICINES, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230234967-A1 | Fused Azole Heterocycles as AHR Antagonists | SAIL BIOMEDICINES, INC. | 2023-07-27 | — | — | US | disclosed |
| CN-112004863-B | Aqueous dispersion of cellulose nanofibers | 旭化成株式会社 | 2023-07-14 | — | — | CN | disclosed |
| US-11685732-B2 | MYST family histone acetyltransferase inhibitors | Epizyme, Inc. (US) | 2023-06-27 | — | — | US | disclosed |
| US-20230103791-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-04-06 | — | — | US | disclosed |
| US-20070004726-A1 | Pharmaceutical/cosmetic compositions comprising novel ligands that activate RAR receptors | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2007-01-04 | — | — | US | disclosed |
| US-20070004921-A1 | Isopentyl carboxanilides for combating undesired micro-organisms | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-01-04 | — | — | US | disclosed |
| WO-2006076706-A1 | CINNAMIDE AND HYDROCINNAMIDE DERIVATIVES WITH RAF-KINASE INHIBITORY ACTIVITY | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060160803-A1 | Cinnamide and hydrocinnamide derivatives with kinase inhibitory activity | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-07-20 | — | — | US | disclosed |
| EP-1680395-A2 | NOVEL LIGAND ACTIVATING RECEPTORS RARS USED FOR HUMAN MEDICINE AND COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005037772-A2 | NOVEL LIGAND ACTIVATING RECEPTORS RARS USED FOR HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-04-28 | — | — | WO | disclosed |
| CN-1297442-A | 5-aminoindeno [1,2-c] pyrazol-4-ones as anti-cancer and anti-proliferative agents | DU PONT PHARM CO (US) | 2001-05-30 | — | — | CN | disclosed |
| US-4246199-A | ACID CATALYZED REACTION OF A CARBONIUM ION COMPONENT AND A NITRILE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |
| EP-0000059-A1 | Process for the preparation of N-alkyl-substituted carboxamides. | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |
| US-4003735-A | DITHIOCARBAMATES | MONSANTO COMPANY (US) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357208-A1 | MYST FAMILY HISTONE ACETYLTRANSFERASE INHIBITORS | EP300, KAT2A, KAT6A | ALDH1A1 2786/4885HPGD 3438/4885HTT 647/4885 |
| US-11807641-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | ALDH1A1 4709/4885HPGD 4116/4885HTT 2319/4885 |
| US-20230234967-A1 | Fused Azole Heterocycles as AHR Antagonists | AHR, ARNT, AIPL1 | ALDH1A1 799/4885HPGD 148/4885HTT 1468/4885 |
| US-20070004921-A1 | Isopentyl carboxanilides for combating undesired micro-organisms | MLYCD, MRPL21, PGLS | ALDH1A1 498/4885HPGD 3332/4885HTT 4174/4885 |
| US-20060160803-A1 | Cinnamide and hydrocinnamide derivatives with kinase inhibitory activity | MAP3K21, HIPK4, MAP3K20 | ALDH1A1 2863/4885HPGD 1593/4885HTT 769/4885 |
| US-20230103791-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | SCN8A, SCN1A, SCN1B | ALDH1A1 3102/4885HPGD 3374/4885HTT 523/4885 |
| US-11685732-B2 | MYST family histone acetyltransferase inhibitors | EP300, KAT2A, KAT6A | ALDH1A1 2786/4885HPGD 3438/4885HTT 647/4885 |
| US-20070004726-A1 | Pharmaceutical/cosmetic compositions comprising novel ligands that activate RAR receptors | RARA, RARG, RARB | ALDH1A1 153/4885HPGD 1321/4885HTT 4510/4885 |
| US-20240317727-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | HSF1, HSP90AB1, HSP90AA1 | ALDH1A1 2667/4885HPGD 880/4885HTT 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.