Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397731 | 0.95 | TP53 (0.32) | OPRM1OPRD1IKBKBCHUK | |
| SCHEMBL1397655 | 0.92 | MAPT (0.35) | TSHRIKBKBCHUK | |
| SCHEMBL1397538 | 0.89 | THRB (0.32) | IKBKBCHUK | |
| SCHEMBL1397640 | 0.89 | IKBKB (0.38) | OPRM1OPRD1TSHRIKBKBCHUK | |
| SCHEMBL1397802 | 0.89 | MAOB (0.36) | IKBKBCHUK | |
| SCHEMBL1397686 | 0.87 | TP53 (0.35) | IKBKBCHUK | |
| SCHEMBL1397683 | 0.85 | MAPT (0.33) | IKBKBCHUK | |
| SCHEMBL1397462 | 0.83 | CCR2 (0.35) | — | |
| SCHEMBL1397663 | 0.77 | C5AR1 (0.34) | IKBKBCHUK | |
| SCHEMBL1397826 | 0.76 | C5AR1 (0.35) | IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007726-B1 | BENZAMIDE AND HETEROARENE DERIVATIVES AS CETP INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-03-02 | — | — | EP | disclosed |