Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397686 | 0.88 | TP53 (0.35) | MAOB | |
| SCHEMBL1397802 | 0.88 | MAOB (0.36) | MAOB | |
| SCHEMBL1397640 | 0.87 | IKBKB (0.38) | MAOBLMNAHPGD | |
| SCHEMBL1397538 | 0.85 | THRB (0.32) | MAOB | |
| SCHEMBL1397683 | 0.83 | MAPT (0.33) | MAOBHPGD | |
| SCHEMBL1397655 | 0.83 | MAPT (0.35) | MAOB | |
| SCHEMBL1397731 | 0.83 | TP53 (0.32) | MAOB | |
| SCHEMBL1397443 | 0.83 | OPRM1 (0.31) | — | |
| SCHEMBL1385185 | 0.77 | LMNA (0.38) | PPARGPPARDPPARALMNAHPGD | |
| SCHEMBL1397663 | 0.76 | C5AR1 (0.34) | CCR2MAOBNR1I3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007726-B1 | BENZAMIDE AND HETEROARENE DERIVATIVES AS CETP INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-03-02 | — | — | EP | disclosed |