Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TRPM5 | Q9NZQ8 | 3/20 | 0.46 |
| ▸ | TRPM4 | Q8TD43 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SLC8B1 | Q6J4K2 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13981274 | 0.85 | TSHR (0.52) | ATMMEN1KMT2ATRPM5LMNA | |
| SCHEMBL23721282 | 0.83 | LMNA (0.42) | ATMMEN1KMT2ALMNAALB | |
| SCHEMBL1623970 | 0.83 | ATM (0.46) | ATMMEN1KMT2ATRPM5TRPM4 | |
| SCHEMBL7463659 | 0.77 | BRD4 (0.51) | ATMMEN1KMT2ALMNAALB | |
| SCHEMBL1421019 | 0.75 | ATM (0.53) | ATMMEN1KMT2ATRPM5TRPM4 | |
| SCHEMBL9526645 | 0.72 | CCKBR (0.53) | MEN1KMT2A | |
| SCHEMBL9526098 | 0.72 | CCKBR (0.53) | MEN1KMT2A | |
| SCHEMBL8923872 | 0.72 | ATM (0.45) | ATMMEN1KMT2ALMNAALB | |
| SCHEMBL5205016 | 0.71 | ALDH1A1 (0.46) | ATMMEN1KMT2ATRPM5TRPM4 | |
| SCHEMBL21284261 | 0.70 | CHRM1 (0.46) | ATMMEN1KMT2ATRPM5TRPM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008145733-A2 | NOVEL CHEMICAL COMPOUNDS, PRODUCTION THEREOF, AND USE THEREOF | UNIVERSITÄT LEIPZIG (DE) | 2008-12-04 | — | — | WO | disclosed |