Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ITK | Q08881 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16463988 | 0.80 | EHMT2 (0.77) | EHMT2KIF11KDM4EITKMC4R | |
| SCHEMBL13983311 | 0.77 | KIF11 (0.85) | KIF11DRD2TBXA2R | |
| SCHEMBL5359797 | 0.73 | ADORA2A (0.63) | EHMT2ITK | |
| SCHEMBL2725703 | 0.73 | DRD2 (0.53) | EHMT2KIF11ITKDRD2TBXA2R | |
| SCHEMBL9107840 | 0.72 | DRD2 (0.69) | KIF11KDM4EDRD2TBXA2RGAA | |
| SCHEMBL10047980 | 0.71 | DRD2 (0.68) | KIF11DRD2TBXA2RCNR2OPRM1 | |
| SCHEMBL3248338 | 0.70 | EHMT2 (0.53) | EHMT2KIF11ITK | |
| SCHEMBL22121383 | 0.69 | STING1 (0.66) | EHMT2KDM4EITK | |
| SCHEMBL16569005 | 0.69 | EHMT2 (1.00) | EHMT2KDM4EITK | |
| SCHEMBL29349799 | 0.69 | EHMT2 (1.00) | EHMT2KDM4EITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008153701-A1 | COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY | SCHERING CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |