Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16020852 | 0.80 | LMNA (0.47) | LMNAPRKDCALDH1A1PTPN1ERN1 | |
| SCHEMBL13983399 | 0.77 | LPL (0.32) | — | |
| SCHEMBL28095482 | 0.74 | ERN1 (0.50) | LMNAPRKDCALDH1A1TRIM24TYR | |
| SCHEMBL30091707 | 0.72 | LMNA (0.43) | LMNAPRKDCALDH1A1TRIM24TYR | |
| SCHEMBL22272552 | 0.72 | LMNA (0.43) | LMNAPRKDCALDH1A1TRIM24TYR | |
| SCHEMBL13127068 | 0.72 | LTA4H (0.46) | ALDH1A1ERN1SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL15145284 | 0.70 | LMNA (0.59) | LMNAPRKDCALDH1A1TRIM24TYR | |
| SCHEMBL15147553 | 0.70 | GAA (0.47) | LMNAPRKDCALDH1A1TRIM24TYR | |
| SCHEMBL437463 | 0.69 | ALDH1A1 (0.66) | LMNAPRKDCALDH1A1TRIM24TYR | |
| Ethane SCHEMBL28205235 | 0.68 | ALDH1A1 (0.63) | LMNAPRKDCALDH1A1TRIM24TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157726-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |