Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637342 | 0.85 | MMP13 (0.52) | MGLLFAAHACHEMMP13NPC1 | |
| SCHEMBL3637345 | 0.83 | MGLL (0.48) | MGLLFAAHACHECHRM2HPGD | |
| SCHEMBL2843865 | 0.80 | ACHE (0.51) | MGLLFAAHACHEHPGDLMNA | |
| SCHEMBL11388208 | 0.73 | SLC6A3 (0.58) | ACHEHPGDNPC1RAB9AKMT2A | |
| SCHEMBL13984721 | 0.71 | KMT2A (0.45) | MGLLHPGDNPC1LMNARAB9A | |
| SCHEMBL13078740 | 0.71 | ESR1 (0.39) | MGLLKMT2AKDM4E | |
| SCHEMBL3638654 | 0.71 | ACHE (0.47) | ACHECHRM2HPGDLMNAKMT2A | |
| SCHEMBL20198176 | 0.70 | MGLL (0.61) | MGLLFAAHMMP13HPGDNPC1 | |
| SCHEMBL20408672 | 0.68 | MGLL (0.58) | MGLLFAAHMMP13CHRM2HPGD | |
| SCHEMBL18634068 | 0.68 | MGLL (0.55) | MGLLFAAHMMP13CHRM2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |