Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637342 | 0.84 | MMP13 (0.52) | MGLLFAAHALDH1A1L3MBTL1NPC1 | |
| SCHEMBL13984629 | 0.83 | MGLL (0.46) | MGLLFAAHKMT2ACHRM2KDM4E | |
| SCHEMBL2843865 | 0.77 | ACHE (0.51) | MGLLFAAHMEN1KMT2AKDM4E | |
| SCHEMBL3635503 | 0.73 | HSD17B10 (0.43) | MGLLMEN1KMT2ACHRM2KDM4E | |
| SCHEMBL11388208 | 0.72 | SLC6A3 (0.58) | MEN1KMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL20198176 | 0.72 | MGLL (0.61) | MGLLFAAHALDH1A1HPGDL3MBTL1 | |
| SCHEMBL4595366 | 0.71 | RAB9A (0.43) | CHRM2ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL3638654 | 0.70 | ACHE (0.47) | MEN1KMT2ACHRM2KDM4EHPGD | |
| SCHEMBL20408672 | 0.69 | MGLL (0.58) | MGLLFAAHCHRM2KDM4EALDH1A1 | |
| SCHEMBL5285048 | 0.68 | CRHBP (0.52) | MEN1KMT2AKDM4EHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |