Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | C1R | P00736 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13990419 | 0.84 | TAS2R14 (0.51) | CDC25BKDM4EALDH1A1GRIK1FABP4 | |
| SCHEMBL3832897 | 0.84 | FABP4 (0.49) | CDC25BKDM4EPTGS2ALDH1A1MAPT | |
| SCHEMBL13990420 | 0.81 | MPO (0.39) | CDC25BMAPK8PTGS2ALDH1A1MAPT | |
| SCHEMBL13990436 | 0.80 | FABP3 (0.45) | PTGS2ALDH1A1MAPTGRIK1FABP4 | |
| SCHEMBL13990427 | 0.79 | AKR1C3 (0.46) | CDC25BKDM4EALDH1A1MAPTFABP4 | |
| SCHEMBL13990424 | 0.78 | ALDH1A1 (0.46) | KDM4EPTGS2NPC1RAB9AALDH1A1 | |
| SCHEMBL13990448 | 0.78 | GPR35 (0.46) | KDM4ENPC1RAB9AALDH1A1C1R | |
| SCHEMBL13990428 | 0.78 | AKR1C3 (0.47) | CDC25BAKR1B10AKR1B1AKR1C3AKR1C2 | |
| SCHEMBL3834341 | 0.77 | MAPT (0.52) | CDC25BKDM4EMAPTFABP4MEN1 | |
| SCHEMBL13990425 | 0.77 | AKR1C3 (0.56) | CDC25BMEN1KMT2AAKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319175-A1 | Transthyretin Stabilization | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-12-25 | — | — | US | disclosed |
| US-20080319175-A1 | Transthyretin Stabilization | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319175-A1 | Transthyretin Stabilization | TTR, TTPA, ALB | CDC25B 3167/4885KDM4E 3239/4885MAPK8 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.