Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28244973 | 0.76 | LMNA (0.51) | LMNAADORA2ANUDT1AKT1AKT2 | |
| SCHEMBL9910953 | 0.76 | LMNA (0.55) | LMNAHTTGPR3ADORA2ANUDT1 | |
| SCHEMBL16132349 | 0.76 | GPR3 (0.50) | LMNAHTTGPR3NUDT1TSHR | |
| SCHEMBL13222013 | 0.74 | ATM (0.55) | LMNAHTTGPR3NUDT1TSHR | |
| SCHEMBL28945928 | 0.73 | LMNA (0.57) | LMNAHTTGPR3ADORA2ANUDT1 | |
| SCHEMBL16132400 | 0.72 | LCK (0.46) | LMNAGPR3TSHRPDE10AMAPT | |
| SCHEMBL13990854 | 0.71 | LMNA (0.50) | LMNAHTTGPR3ADORA2ANUDT1 | |
| SCHEMBL19161610 | 0.70 | ALDH1A1 (0.45) | LMNAHTTTSHRMAPTMEN1 | |
| SCHEMBL14289088 | 0.70 | GPR3 (0.43) | LMNAHTTGPR3TSHRMEN1 | |
| SCHEMBL28897868 | 0.69 | LMNA (0.43) | LMNAHTTADORA2AAKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312435-A1 | Imine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312435-A1 | Imine Compound | CNR1, CNR2, HRH4 | LMNA 3446/4885HTT 945/4885GPR3 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.