Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28920770 | 0.83 | ATM (0.44) | ATMKDM4EALDH1A1HPGDGLA | |
| SCHEMBL14506374 | 0.81 | ATM (0.43) | ATMKDM4EALDH1A1HPGDGLA | |
| SCHEMBL21791642 | 0.81 | TYMS (0.44) | ATMKDM4EALDH1A1HPGDGLA | |
| SCHEMBL24604916 | 0.81 | DHODH (0.41) | ATMKDM4EALDH1A1POLBELANE | |
| SCHEMBL16801733 | 0.81 | MAOA (0.50) | ATMALDH1A1POLBHSD17B10MAOA | |
| SCHEMBL30849704 | 0.79 | CYP1A2 (0.40) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16132394 | 0.78 | GPR3 (0.50) | ATMKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL5720497 | 0.78 | KDM4E (0.52) | ATMKDM4EALDH1A1HPGDGLA | |
| SCHEMBL5720410 | 0.76 | MAOA (0.56) | ATMKDM4EALDH1A1HPGDGLA | |
| SCHEMBL16132377 | 0.76 | GPR3 (0.47) | ATMKDM4EALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372309-A1 | ALPHA-2 ADRENERGIC RECEPTOR ANTAGONIST | KYOTO UNIVERSITY (JP) | 2023-11-23 | — | — | US | disclosed |
| US-20230372309-A1 | ALPHA-2 ADRENERGIC RECEPTOR ANTAGONIST | KYOTO UNIVERSITY (JP) | 2023-11-23 | — | — | US | disclosed |
| US-11690850-B2 | Inhibitors of receptor interacting protein kinase I for the treatment of disease | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-04 | — | — | US | disclosed |
| US-11690850-B2 | Inhibitors of receptor interacting protein kinase I for the treatment of disease | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-04 | — | — | US | disclosed |
| US-20230038201-A1 | TRANSFER FILM, PHOTOSENSITIVE MATERIAL, PATTERN FORMING METHOD, MANUFACTURING METHOD OF CIRCUIT BOARD, AND MANUFACTURING METHOD OF TOUCH PANEL | FUJIFILM CORPORATION (JP) | 2023-02-09 | — | — | US | disclosed |
| US-20220216426-A1 | NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2022-07-07 | — | — | US | disclosed |
| US-20210154204-A1 | INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2021-05-27 | — | — | US | disclosed |
| US-20200251662-A1 | THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY PANEL | Wuhan China Star Optoelectronics Semicondutor Display Technology Co., Ltd. (CN) | 2020-08-06 | — | — | US | disclosed |
| US-20200071276-A1 | Acridine Compound for Use in an Electronic Device and Display Device | NOVALED GMBH (DE) | 2020-03-05 | — | — | US | disclosed |
| US-10035765-B2 | Nitrogen-containing polycyclic compound and organic light emitting device using same | LG CHEM, LTD. (KR) | 2018-07-31 | — | — | US | disclosed |
| US-20170283379-A1 | NITROGEN-CONTAINING POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME (AS AMENDED) | LG CHEM, LTD. (KR) | 2017-10-05 | — | — | US | disclosed |
| US-20170283379-A1 | NITROGEN-CONTAINING POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME (AS AMENDED) | LG CHEM, LTD. (KR) | 2017-10-05 | — | — | US | disclosed |
| US-20170152260-A1 | STAT3 INHIBITOR | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-06-01 | — | — | US | disclosed |
| US-20170152260-A1 | STAT3 INHIBITOR | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-06-01 | — | — | US | disclosed |
| US-9562002-B2 | STAT3 inhibitor | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-02-07 | — | — | US | disclosed |
| US-9562002-B2 | STAT3 inhibitor | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-02-07 | — | — | US | disclosed |
| US-20150361031-A1 | STAT3 INHIBITOR | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-12-17 | — | — | US | disclosed |
| US-9133115-B2 | 4-amino-4-oxobutanoyl peptides as inhibitors of viral replication | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-09-15 | — | — | US | disclosed |
| US-20140113890-A1 | NEW 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2014-04-24 | — | — | US | disclosed |
| US-20100216725-A1 | 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11690850-B2 | Inhibitors of receptor interacting protein kinase I for the treatment of disease | RIPK1, RIPK2, RIPK4 | ATM 869/4885KDM4E 3689/4885ALDH1A1 4554/4885 |
| US-20230372309-A1 | ALPHA-2 ADRENERGIC RECEPTOR ANTAGONIST | ADRA2A, ADRB2, ADRA2B | ATM 4176/4885KDM4E 4114/4885ALDH1A1 407/4885 |
| US-20170283379-A1 | NITROGEN-CONTAINING POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME (AS AMENDED) | PER2, CRY1, CRY2 | ATM 1605/4885KDM4E 1594/4885ALDH1A1 1815/4885 |
| US-20200251662-A1 | THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY PANEL | TEAD2, TEAD1, TEAD3 | ATM 1079/4885KDM4E 3584/4885ALDH1A1 115/4885 |
| US-20210154204-A1 | INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE | RIPK1, RIPK2, RIPK4 | ATM 869/4885KDM4E 3689/4885ALDH1A1 4554/4885 |
| US-20140113890-A1 | NEW 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION | ZC3HAV1, VIP, ZC3HAV1L | ATM 4864/4885KDM4E 556/4885ALDH1A1 4204/4885 |
| US-20170152260-A1 | STAT3 INHIBITOR | STAT3, STAT1, STAT4 | ATM 377/4885KDM4E 3388/4885ALDH1A1 2922/4885 |
| US-20100216725-A1 | 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION | ZC3HAV1, VIP, O60361 | ATM 4855/4885KDM4E 493/4885ALDH1A1 4184/4885 |
| US-20200071276-A1 | Acridine Compound for Use in an Electronic Device and Display Device | ACR, ALDH1A1, TRPA1 | ATM 1394/4885KDM4E 3497/4885ALDH1A1 2/4885 |
| US-20220216426-A1 | NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS | NCL, DNMT3A, NUDT1 | ATM 666/4885KDM4E 3514/4885ALDH1A1 1167/4885 |
| US-20150361031-A1 | STAT3 INHIBITOR | STAT3, STAT1, STAT4 | ATM 377/4885KDM4E 3388/4885ALDH1A1 2922/4885 |
| US-10035765-B2 | Nitrogen-containing polycyclic compound and organic light emitting device using same | NPM1, PER2, CRY1 | ATM 2242/4885KDM4E 1641/4885ALDH1A1 2342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.