Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13207809 | 1.00 | CHRNA7 (0.39) | CHRNA7ALOX5CYP2A6LMNAHIF1A | |
| SCHEMBL4143616 | 0.79 | ADRA2A (0.54) | LMNAHIF1AKDM4EADRA2AADRA2C | |
| SCHEMBL12598166 | 0.79 | ADRA2A (0.54) | LMNAHIF1AKDM4EADRA2AADRA2C | |
| SCHEMBL13995149 | 0.79 | CHRNA7 (0.41) | CHRNA7ALOX5CYP2A6LMNAALDH1A1 | |
| SCHEMBL18211567 | 0.78 | LMNA (0.44) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL18973797 | 0.77 | ACP3 (0.43) | LMNAHIF1AKDM4EADRA2AADRA2C | |
| SCHEMBL11938485 | 0.75 | CHRNA7 (0.55) | CHRNA7ALOX5LMNAHIF1AKDM4E | |
| SCHEMBL3693273 | 0.75 | CHRNA7 (0.55) | CHRNA7ALOX5LMNAHIF1AKDM4E | |
| SCHEMBL11938483 | 0.75 | CHRNA7 (0.55) | CHRNA7ALOX5LMNAHIF1AKDM4E | |
| SCHEMBL18660867 | 0.74 | KDM4E (0.64) | CHRNA7ALOX5LMNAHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319200-A1 | PROCESS FOR PREPARING OXAZOLINE-PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | SCHERING-PLOUGH ANIMAL HEALTH CORP. | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319200-A1 | PROCESS FOR PREPARING OXAZOLINE-PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | PFAS, DHFR, DDC | CHRNA7 2773/4885ALOX5 882/4885CYP2A6 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.