Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3612939 | 0.81 | HDAC6 (0.57) | HSD17B10ALDH1A1HDAC1HDAC6KDM4E | |
| SCHEMBL14005185 | 0.81 | TSHR (0.57) | MAPTTSHRRECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL14025800 | 0.81 | MAPT (0.66) | MAPTTSHRRECQLSMN1; SMN2THRB | |
| SCHEMBL3604538 | 0.80 | HSD17B10 (0.56) | TSHRRECQLHSD17B10SMN1; SMN2THRB | |
| SCHEMBL7080320 | 0.78 | MAPT (0.73) | MAPTTSHRRECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL18782204 | 0.78 | SLC40A1 (0.59) | MAPTTSHRRECQLTHRBL3MBTL1 | |
| SCHEMBL14025441 | 0.77 | SMN1; SMN2 (0.64) | MAPTTSHRRECQLSMN1; SMN2L3MBTL1 | |
| SCHEMBL1793590 | 0.77 | ALDH1A1 (0.66) | MAPTTSHRRECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL14025799 | 0.77 | ITGB3 (0.53) | HSD17B10SMN1; SMN2ITGB3ITGAVALDH1A1 | |
| SCHEMBL14025811 | 0.75 | HSD17B10 (0.46) | TSHRRECQLHSD17B10SMN1; SMN2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809846-B2 | Organic molecular memories and organic molecules for organic molecular memories | KABUSHIKI KAISHA TOSHIBA (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | CCR5, CCL2, CXCR4 | MAPT 4253/4885TSHR 2114/4885RECQL 3705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.