Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | VNN1 | O95497 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PRKCG | P05129 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4636511 | 0.80 | HPGDS (1.00) | HPGDSL3MBTL1HDAC2HDAC3HDAC1 | |
| SCHEMBL5077115 | 0.80 | HPGDS (0.67) | HPGDSL3MBTL1HDAC2HDAC1HDAC6 | |
| SCHEMBL14005266 | 0.79 | RAB9A (0.55) | HPGD | |
| SCHEMBL14005267 | 0.77 | MAPT (0.54) | L3MBTL1 | |
| SCHEMBL14029902 | 0.77 | CNR2 (0.52) | HPGDSL3MBTL1HPGD | |
| SCHEMBL5077152 | 0.77 | HPGDS (0.67) | HPGDSL3MBTL1HDAC2HDAC3HDAC1 | |
| SCHEMBL4745657 | 0.76 | CNR2 (0.76) | — | |
| SCHEMBL13210567 | 0.76 | L3MBTL1 (0.76) | HPGDSL3MBTL1HDAC2HDAC6HDAC8 | |
| SCHEMBL10077690 | 0.76 | L3MBTL1 (0.71) | HPGDSL3MBTL1HDAC2HDAC1HDAC6 | |
| SCHEMBL457082 | 0.75 | HDAC6 (0.79) | HDAC2HDAC1HDAC6HDAC8ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | CCR5, CCL2, CXCR4 | HPGDS 51/4885L3MBTL1 4465/4885HDAC2 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.