Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | KYNU | Q16719 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1263253 | 0.98 | ALOX5AP (0.38) | ALOX5APFEN1KYNULOXL2PNMT | |
| SCHEMBL4598904 | 0.81 | PSIP1 (0.45) | LOXL2PNMTCA2DPP4CTSB | |
| Hydrochloric Acid SCHEMBL7370334 | 0.79 | LOXL2 (0.44) | LOXL2PNMTCA2DPP4CTSB | |
| SCHEMBL11180737 | 0.78 | MMP2 (0.51) | KYNU | |
| SCHEMBL14008635 | 0.78 | LOXL2 (0.38) | ALOX5APFEN1LOXL2PNMTDPP4 | |
| SCHEMBL5264466 | 0.78 | KYNU (0.60) | ALOX5APFEN1KYNUCA2 | |
| Hydrochloric Acid SCHEMBL28787363 | 0.77 | LOXL2 (0.33) | LOXL2CA2 | |
| SCHEMBL14009378 | 0.76 | LOXL2 (0.40) | ALOX5APFEN1LOXL2PNMTDPP4 | |
| Hydrochloric Acid SCHEMBL1262777 | 0.76 | LOXL2 (0.39) | ALOX5APFEN1LOXL2PNMTCA2 | |
| SCHEMBL4697110 | 0.76 | ALOX5AP (0.39) | ALOX5APFEN1KYNUPTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456195-B2 | Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-25 | — | — | US | disclosed |
| US-20070003539-A1 | Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070003539-A1 | Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants | F12, F11, F7 | ALOX5AP 2953/4885FEN1 2018/4885KYNU 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.