Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5091881 | 0.85 | ACHE (0.46) | ACHEGSK3BBACE1DRD2DRD3 | |
| SCHEMBL5091017 | 0.83 | ABCB1 (0.43) | ACHEGSK3BBACE1CYP11B1CYP11B2 | |
| SCHEMBL14015556 | 0.81 | CYP11B2 (0.38) | ACHEGSK3BBACE1CYP11B1CYP11B2 | |
| SCHEMBL5103707 | 0.81 | ACHE (0.38) | ACHEGSK3BBACE1CYP11B1CYP11B2 | |
| SCHEMBL5094857 | 0.80 | PARP1 (0.39) | ACHEGSK3BBACE1CYP11B1CYP11B2 | |
| SCHEMBL5091955 | 0.79 | DRD2 (0.49) | ACHEGSK3BCYP11B1CYP11B2DRD2 | |
| SCHEMBL27706460 | 0.75 | CYP11B1 (0.38) | BACE1CYP11B1CYP11B2TNIK | |
| SCHEMBL5094873 | 0.75 | CYP1A2 (0.43) | CYP11B1CYP11B2WNT1DYRK1AMKNK1 | |
| SCHEMBL5094777 | 0.75 | ACHE (0.44) | ACHEGSK3BBACE1WNT1DYRK1A | |
| SCHEMBL5096924 | 0.74 | PIK3CA (0.43) | CYP11B1CYP11B2DRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306111-A1 | TRICYCLIC DELTA- OPIOID MODULATORS | CARSON JOHN R | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306111-A1 | TRICYCLIC DELTA- OPIOID MODULATORS | OPRD1, OPRK1, OPRL1 | ACHE 303/4885GSK3B 594/4885BACE1 2686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.