Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5092091 | 0.88 | BACE1 (0.43) | BACE1APPESR1GAAFGFR1 | |
| SCHEMBL11445353 | 0.81 | BACE1 (0.49) | BACE1APPESR1FGFR1ACHE | |
| Hydrochloric Acid SCHEMBL11433671 | 0.80 | BACE1 (0.47) | BACE1APPESR1FGFR1ACHE | |
| SCHEMBL14882515 | 0.75 | TDP1 (0.43) | GAAMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL14013395 | 0.74 | ALDH1A1 (0.43) | PPARAFFAR4FGFR1SLC16A3SLC16A1 | |
| SCHEMBL3994473 | 0.73 | LTA4H (0.46) | APP | |
| SCHEMBL12061824 | 0.72 | ALOX5 (0.40) | ACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL9123171 | 0.71 | LMNA (0.44) | PPARAESR1CYSLTR2CYSLTR1FFAR4 | |
| SCHEMBL2424467 | 0.69 | ALDH1A1 (0.42) | GAAMEN1KMT2AALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11387842 | 0.69 | BACE1 (0.36) | BACE1APPESR1FGFR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210041465-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2021-02-11 | — | — | US | disclosed |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2020-11-24 | — | — | US | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9910051-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-03-06 | — | — | US | disclosed |
| US-9910051-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-03-06 | — | — | US | disclosed |
| US-20160139158-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-05-19 | — | — | US | disclosed |
| US-20160139158-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-05-19 | — | — | US | disclosed |
| US-20150037834-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2015-02-05 | — | — | US | disclosed |
| US-20150037834-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2015-02-05 | — | — | US | disclosed |
| EP-2727965-A1 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2014-05-07 | — | — | EP | disclosed |
| EP-2064290-B1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2013-10-09 | — | — | EP | disclosed |
| US-20130102021-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102021-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2013-04-25 | — | — | US | disclosed |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-11-06 | — | — | US | disclosed |
| WO-2008076524-A2 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | BACE1 3226/4885PPARA 4228/4885POLB 4360/4885 |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | SLC11A2, MAN2B1, CD47 | BACE1 3226/4885PPARA 4228/4885POLB 4360/4885 |
| US-20210041465-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | BACE1 3226/4885PPARA 4228/4885POLB 4360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.