Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14038445 | 0.86 | THRA (0.47) | LTA4H | |
| SCHEMBL3993241 | 0.83 | MAOB (0.53) | NOX1APP | |
| SCHEMBL5092091 | 0.81 | BACE1 (0.43) | APP | |
| SCHEMBL14882515 | 0.79 | TDP1 (0.43) | — | |
| SCHEMBL2502826 | 0.77 | TSHR (0.44) | — | |
| SCHEMBL3991363 | 0.77 | TSPO (0.50) | APP | |
| SCHEMBL9046522 | 0.76 | ALDH1A1 (0.52) | NOX1MTNR1A | |
| SCHEMBL17030789 | 0.75 | PDE3B (0.40) | LTA4HMTNR1A | |
| SCHEMBL16985198 | 0.74 | ALDH1A1 (0.41) | LTA4HMTNR1A | |
| SCHEMBL14013331 | 0.73 | LTA4H (0.40) | LTA4HMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11867698-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2024-01-09 | — | — | US | disclosed |
| US-20210041465-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2021-02-11 | — | — | US | disclosed |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2020-11-24 | — | — | US | disclosed |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2020-11-24 | — | — | US | disclosed |
| US-20180238912-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2018-08-23 | — | — | US | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9910051-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-03-06 | — | — | US | disclosed |
| US-9910051-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-03-06 | — | — | US | disclosed |
| US-20160139158-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-05-19 | — | — | US | disclosed |
| US-20150037834-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2015-02-05 | — | — | US | disclosed |
| EP-2727965-A1 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2014-05-07 | — | — | EP | disclosed |
| EP-2064290-B1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2013-10-09 | — | — | EP | disclosed |
| US-20130102021-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2013-04-25 | — | — | US | disclosed |
| EP-2064290-A2 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-11-06 | — | — | US | disclosed |
| WO-2008076524-A2 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180238912-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | LTA4H 243/4885NOX1 138/4885APP 2658/4885 |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | LTA4H 243/4885NOX1 138/4885APP 2658/4885 |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | SLC11A2, MAN2B1, CD47 | LTA4H 243/4885NOX1 138/4885APP 2658/4885 |
| US-20210041465-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | LTA4H 243/4885NOX1 138/4885APP 2658/4885 |
| US-11867698-B2 | Fluorogenic pH sensitive dyes and their method of use | SLC11A2, MAN2B1, CD47 | LTA4H 243/4885NOX1 138/4885APP 2658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.