Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14013418 | 0.88 | BACE1 (0.41) | BACE1APPESR1FGFR1ALDH1A1 | |
| SCHEMBL14882515 | 0.87 | TDP1 (0.43) | MAPTTOP2AALDH1A1GAAHTT | |
| SCHEMBL14038445 | 0.83 | THRA (0.47) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL3994473 | 0.81 | LTA4H (0.46) | APP | |
| SCHEMBL11445353 | 0.80 | BACE1 (0.49) | BACE1APPMAPTESR1FGFR1 | |
| Hydrochloric Acid SCHEMBL11433671 | 0.79 | BACE1 (0.47) | BACE1APPMAPTESR1FGFR1 | |
| SCHEMBL2502826 | 0.78 | TSHR (0.44) | MAPTALDH1A1GAAHTTKMT2A | |
| SCHEMBL12061824 | 0.76 | ALOX5 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2424467 | 0.76 | ALDH1A1 (0.42) | MAPTALDH1A1GAAHTTNPSR1 | |
| SCHEMBL17030789 | 0.75 | PDE3B (0.40) | MAPTALDH1A1GAAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11867698-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2024-01-09 | — | — | US | disclosed |
| US-20210041465-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2021-02-11 | — | — | US | disclosed |
| US-20210041465-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2021-02-11 | — | — | US | disclosed |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2020-11-24 | — | — | US | disclosed |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2020-11-24 | — | — | US | disclosed |
| US-20180238912-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2018-08-23 | — | — | US | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9910051-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-03-06 | — | — | US | disclosed |
| EP-2727965-A1 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2014-05-07 | — | — | EP | disclosed |
| EP-2064290-B1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2013-10-09 | — | — | EP | disclosed |
| EP-2064290-B1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2013-10-09 | — | — | EP | disclosed |
| US-20130102021-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102021-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102021-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2013-04-25 | — | — | US | disclosed |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-11-06 | — | — | US | disclosed |
| WO-2008076524-A2 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180238912-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | BACE1 3226/4885APP 2658/4885MAPT 3982/4885 |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | BACE1 3226/4885APP 2658/4885MAPT 3982/4885 |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | SLC11A2, MAN2B1, CD47 | BACE1 3226/4885APP 2658/4885MAPT 3982/4885 |
| US-20210041465-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | BACE1 3226/4885APP 2658/4885MAPT 3982/4885 |
| US-11867698-B2 | Fluorogenic pH sensitive dyes and their method of use | SLC11A2, MAN2B1, CD47 | BACE1 3226/4885APP 2658/4885MAPT 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.