Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | IL6 | P05231 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639358 | 0.95 | KMT2A (0.37) | DRD2FAAHDRD3IL6LMNA | |
| SCHEMBL13639336 | 0.91 | HCRTR1 (0.37) | DRD2FAAHDRD3IL6LMNA | |
| SCHEMBL14015835 | 0.90 | IL6 (0.39) | DRD2FAAHDRD3IL6LMNA | |
| SCHEMBL13639363 | 0.89 | KMT2A (0.38) | DRD2FAAHDRD3IL6MAPT | |
| SCHEMBL14015597 | 0.89 | MAPT (0.48) | LMNAMAPTALDH1A1HTTTDP1 | |
| SCHEMBL13639362 | 0.89 | HTR1A (0.37) | DRD2FAAHDRD3IL6LMNA | |
| SCHEMBL13639370 | 0.88 | IL6 (0.38) | DRD2FAAHDRD3IL6MAPT | |
| SCHEMBL13639326 | 0.86 | IL6 (0.38) | DRD2IL6LMNAMAPTHTR1A | |
| SCHEMBL14015605 | 0.86 | KMT2A (0.36) | IL6LMNAMAPTHTR1AALDH1A1 | |
| SCHEMBL14878774 | 0.86 | ALOX15 (0.41) | DRD2IL6LMNAMAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995242-A1 | NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | Santen Pharmaceutical Co., Ltd (JP) | 2008-11-26 | — | — | EP | disclosed |