Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL30750875 | 0.83 | SLC1A1 (0.48) | TSHRTP53EGLN1EGLN3GABRP | |
| Maleic Acid SCHEMBL29755662 | 0.83 | SLC1A1 (0.48) | TSHRTP53EGLN1EGLN3GABRP | |
| Fumaric Acid SCHEMBL31501165 | 0.81 | SLC1A1 (0.46) | TSHRTP53EGLN1EGLN3GABRP | |
| SCHEMBL5070678 | 0.79 | PTGS1 (0.52) | TSHRTP53EGLN1EGLN3GABRP | |
| SCHEMBL4135917 | 0.76 | — | — | |
| Fumaric Acid SCHEMBL10400867 | 0.75 | GABRP (0.54) | TSHRTP53EGLN1EGLN3GABRP | |
| SCHEMBL1401888 | 0.73 | GSR (0.59) | MEN1KMT2A | |
| Maleic Acid SCHEMBL4623286 | 0.73 | TSHR (0.69) | TSHRTP53EGLN1EGLN3GABRP | |
| SCHEMBL29498253 | 0.72 | — | — | |
| SCHEMBL1633647 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180346629-A1 | Biocompatible polymers and co-polymers, and uses thereof | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2018-12-06 | — | — | US | disclosed |
| EP-2292672-B1 | Biocompatible polymers and co-polymers comprising amino acids in the side chain | CIS PHARMA AG (CH) | 2018-05-09 | — | — | EP | disclosed |
| US-9839719-B2 | Biocompatible polymers and co-polymers, and uses thereof | CIS PHARMA AG (CH) | 2017-12-12 | — | — | US | disclosed |
| US-20170152335-A1 | Biocompatible polymers and co-polymers, and uses thereof | HITZ HANS (CH) | 2017-06-01 | — | — | US | disclosed |
| EP-1888660-B1 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CIS PHARMA AG (CH) | 2017-05-17 | — | — | EP | disclosed |
| EP-2292672-A2 | Biocompatible polymers and co-polymers comprising amino acids in the side chain | Chemisches Institut Schaefer AG (CH) | 2011-03-09 | — | — | EP | disclosed |
| US-20090232871-A1 | Biocompatible polymers and co-polymers, and uses thereof | HITZ HANS | 2009-09-17 | — | — | US | disclosed |
| EP-1888660-A2 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | Chemisches Institut Schaefer AG (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006126095-A2 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CHEMISCHES INSTITUT SCHAEFER AG (CH) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090232871-A1 | Biocompatible polymers and co-polymers, and uses thereof | PPIH, ARG1, P4HA1 | TSHR 4255/4885TP53 4063/4885EGLN1 594/4885 |
| US-20170152335-A1 | Biocompatible polymers and co-polymers, and uses thereof | ARG1, CRYAA, COL1A1 | TSHR 4182/4885TP53 3200/4885EGLN1 2027/4885 |
| US-20180346629-A1 | Biocompatible polymers and co-polymers, and uses thereof | ARG1, CRYAA, COL1A1 | TSHR 4182/4885TP53 3200/4885EGLN1 2027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.