Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.55 |
| ▸ | CES2 | O00748 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20284 | 0.94 | — | — | |
| SCHEMBL28855277 | 0.94 | CES1 (0.61) | CES1CES2TP53SOAT1MEN1 | |
| Acetic Acid SCHEMBL27601436 | 0.92 | CES1 (0.52) | CES1CES2TP53SOAT1MEN1 | |
| SCHEMBL9473171 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL4188396 | 0.91 | — | — | |
| Bromide SCHEMBL30200144 | 0.91 | — | — | |
| SCHEMBL106748 | 0.91 | — | — | |
| SCHEMBL4135496 | 0.91 | — | — | |
| SCHEMBL5829952 | 0.91 | — | — | |
| SCHEMBL29959512 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180346629-A1 | Biocompatible polymers and co-polymers, and uses thereof | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2018-12-06 | — | — | US | claimed |
| EP-2292672-B1 | Biocompatible polymers and co-polymers comprising amino acids in the side chain | CIS PHARMA AG (CH) | 2018-05-09 | — | — | EP | claimed |
| US-20170152335-A1 | Biocompatible polymers and co-polymers, and uses thereof | HITZ HANS (CH) | 2017-06-01 | — | — | US | claimed |
| EP-1888660-B1 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CIS PHARMA AG (CH) | 2017-05-17 | — | — | EP | claimed |
| US-8980957-B2 | Methods for the preparation of biocompatible polymers, the polymers and their uses | CIS PHARMA AG (CH) | 2015-03-17 | — | — | US | claimed |
| US-20140242722-A1 | ARTICLE AND METHOD FOR DETECTION OF A DRUG IN A LIQUID MEDIUM | MEDTECH DETECT, LLC (US) | 2014-08-28 | — | — | US | claimed |
| WO-2014062910-A1 | SPIROPYRAN-BASED COLORIMETRIC DETECTION | MEDTECH DETECT, LLC (US) | 2014-04-24 | — | — | WO | claimed |
| US-20120329902-A1 | METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES | SCHAEFER ROLF (CH) | 2012-12-27 | — | — | US | claimed |
| EP-2523982-A1 | METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES | Chemisches Institut Schaefer AG (CH) | 2012-11-21 | — | — | EP | claimed |
| WO-2011085988-A1 | METHODS FOR THE PREPARATION OF BIOCOMPATIBLE POLYMERS, THE POLYMERS AND THEIR USES | CHEMISCHES INSTITUT SCHAEFER AG (CH) | 2011-07-21 | — | — | WO | claimed |
| EP-2292672-A2 | Biocompatible polymers and co-polymers comprising amino acids in the side chain | Chemisches Institut Schaefer AG (CH) | 2011-03-09 | — | — | EP | claimed |
| US-20090232871-A1 | Biocompatible polymers and co-polymers, and uses thereof | HITZ HANS | 2009-09-17 | — | — | US | claimed |
| EP-1888660-A2 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | Chemisches Institut Schaefer AG (CH) | 2008-02-20 | — | — | EP | claimed |
| WO-2006126095-A2 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CHEMISCHES INSTITUT SCHAEFER AG (CH) | 2006-11-30 | — | — | WO | claimed |
| US-11008414-B2 | Polymer materials for contact lens applications | CIS PHARMA AG (CH) | 2021-05-18 | — | — | US | disclosed |
| US-20200283560-A1 | New polymer materials for contact lens applications | CIS PHARMA AG (CH) | 2020-09-10 | — | — | US | disclosed |
| EP-3356433-B1 | NEW POLYMER MATERIALS FOR CONTACT LENS APPLICATIONS | CIS PHARMA AG (CH) | 2019-09-18 | — | — | EP | disclosed |
| US-20090232871-A1 | Biocompatible polymers and co-polymers, and uses thereof | HITZ HANS | 2009-09-17 | — | — | US | disclosed |
| EP-1888660-A2 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | Chemisches Institut Schaefer AG (CH) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006126095-A2 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CHEMISCHES INSTITUT SCHAEFER AG (CH) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090232871-A1 | Biocompatible polymers and co-polymers, and uses thereof | PPIH, ARG1, P4HA1 | CES1 1495/4885CES2 953/4885TP53 4063/4885 |
| US-20170152335-A1 | Biocompatible polymers and co-polymers, and uses thereof | ARG1, CRYAA, COL1A1 | CES1 2857/4885CES2 3137/4885TP53 3200/4885 |
| US-20200283560-A1 | New polymer materials for contact lens applications | CRYAA, CRYAB, BCAT1 | CES1 3397/4885CES2 2692/4885TP53 1746/4885 |
| US-11008414-B2 | Polymer materials for contact lens applications | CRYAA, BCAT1, CRYAB | CES1 3323/4885CES2 2457/4885TP53 1317/4885 |
| US-20180346629-A1 | Biocompatible polymers and co-polymers, and uses thereof | ARG1, CRYAA, COL1A1 | CES1 2857/4885CES2 3137/4885TP53 3200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.