Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4888710 | 0.88 | TP53 (0.46) | RNASEH1MAPTPOLBALDH1A1L3MBTL1 | |
| SCHEMBL26616480 | 0.85 | CES1 (0.49) | RNASEH1POLBTARBP2LMNATP53 | |
| SCHEMBL28356660 | 0.82 | RNASEH1 (0.41) | RNASEH1MAPTTARBP2ALDH1A1L3MBTL1 | |
| SCHEMBL1461721 | 0.81 | ATM (0.47) | MAPTTARBP2L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL14019445 | 0.80 | ALDH1A1 (0.47) | RNASEH1MAPTPOLBALDH1A1KDM4E | |
| SCHEMBL28353287 | 0.77 | MAPT (0.47) | RNASEH1MAPTPOLBALDH1A1L3MBTL1 | |
| SCHEMBL12377784 | 0.77 | NPSR1 (0.47) | TARBP2ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL17162432 | 0.75 | NPSR1 (0.45) | TARBP2ALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL17761179 | 0.75 | HCRTR1 (0.50) | TARBP2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL2778345 | 0.75 | TARBP2 (0.70) | MAPTPOLBTARBP2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | PAH, TST, MPST | RNASEH1 2362/4885MAPT 1228/4885POLB 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.