Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019442 | 0.88 | RNASEH1 (0.52) | TP53MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4884202 | 0.76 | NPC1 (0.42) | TP53MAPTSMN1; SMN2ACSL1MEN1 | |
| SCHEMBL4887366 | 0.74 | SLC26A6 (0.46) | MAPTSMN1; SMN2ACSL1KMT2ANPC1 | |
| SCHEMBL12377784 | 0.74 | NPSR1 (0.47) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL28356660 | 0.73 | RNASEH1 (0.41) | TP53MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL14259046 | 0.73 | BRD4 (0.52) | TP53MAPTSMN1; SMN2THRBMEN1 | |
| SCHEMBL12797648 | 0.73 | LOXL2 (0.64) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL1461721 | 0.73 | ATM (0.47) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL17162432 | 0.72 | NPSR1 (0.45) | SMN1; SMN2MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL8993120 | 0.72 | MAPT (0.56) | TP53MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| EP-1742942-A1 | PHENYLTHIOACETIC ACID DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005097784-A1 | PHENYLTHIOACETIC ACID DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | PAH, TST, MPST | TP53 3026/4885MAPT 1228/4885SMN1; SMN2 4675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.